Gene signature and connectivity mapping to assist with drug prediction for pancreatic ductal adenocarcinoma
Y Xiao, B Zhang, JM Cloyd, G Xu, S Du, Y Mao… - Surgical Oncology, 2022 - Elsevier
Introduction The prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) is
highly variable and there is a paucity of effective treatment options for patients with PDAC …
highly variable and there is a paucity of effective treatment options for patients with PDAC …
[HTML][HTML] PDAC-ANN: an artificial neural network to predict pancreatic ductal adenocarcinoma based on gene expression
PP Almeida, CP Cardoso, LM de Freitas - BMC cancer, 2020 - Springer
Background Although the pancreatic ductal adenocarcinoma (PDAC) presents high mortality
and metastatic potential, there is a lack of effective therapies and a low survival rate for this …
and metastatic potential, there is a lack of effective therapies and a low survival rate for this …
[HTML][HTML] Identification of key pathways and candidate genes in pancreatic ductal adenocarcinoma using bioinformatics analysis
Y He, Y Liu, J Gong, C Liu, H Zhang… - Oncology …, 2019 - spandidos-publications.com
Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor with a high degree of
malignancy that is difficult to diagnose and treat. The present study integrated PDAC cohort …
malignancy that is difficult to diagnose and treat. The present study integrated PDAC cohort …
[HTML][HTML] Identification of potential target genes in pancreatic ductal adenocarcinoma by bioinformatics analysis
Y Tang, Z Zhang, Y Tang, X Chen… - Oncology …, 2018 - spandidos-publications.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most complicated and fatally
pathogenic human malignancies. Therefore, there is an urgent need to improve our …
pathogenic human malignancies. Therefore, there is an urgent need to improve our …
Integrated bioinformatics analysis of potential biomarkers for pancreatic cancer
H Shi, H Xu, C Chai, Z Qin… - Journal of Clinical …, 2022 - Wiley Online Library
Background Pancreatic cancer, particularly pancreatic ductal adenocarcinoma (PDA), is an
aggressive malignancy associated with a low 5‐year survival rate. Poor outcomes …
aggressive malignancy associated with a low 5‐year survival rate. Poor outcomes …
[HTML][HTML] Identifying drug targets in pancreatic ductal adenocarcinoma through machine learning, analyzing biomolecular networks, and structural modeling
W Yan, X Liu, Y Wang, S Han, F Wang, X Liu… - Frontiers in …, 2020 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related
death and has an extremely poor prognosis. Thus, identifying new disease-associated …
death and has an extremely poor prognosis. Thus, identifying new disease-associated …
[HTML][HTML] The identification of liver metastasis-and prognosis-associated genes in pancreatic ductal adenocarcinoma
H Luan, Y He, T Zhang, Y Su, L Zhou - BMC cancer, 2022 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) is an often fatal malignancy with an
extremely low survival rate. Liver metastasis, which causes high mortality, is the most …
extremely low survival rate. Liver metastasis, which causes high mortality, is the most …
[HTML][HTML] A comprehensive meta-analysis of transcriptome data to identify signature genes associated with pancreatic ductal adenocarcinoma
SO Kordshouli, A Tahmasebi, A Moghadam… - Plos one, 2024 - journals.plos.org
Purpose Pancreatic ductal adenocarcinoma (PDAC) has a five-year survival rate of less than
5%. Absence of symptoms at primary tumor stages, as well as high aggressiveness of the …
5%. Absence of symptoms at primary tumor stages, as well as high aggressiveness of the …
[HTML][HTML] Identification and validation of a diagnostic and prognostic multi-gene biomarker panel for pancreatic ductal adenocarcinoma
H Klett, H Fuellgraf, E Levit-Zerdoun, S Hussung… - Frontiers in …, 2018 - frontiersin.org
Late diagnosis and systemic dissemination essentially contribute to the invariably poor
prognosis of pancreatic ductal adenocarcinoma (PDAC). Therefore, the development of …
prognosis of pancreatic ductal adenocarcinoma (PDAC). Therefore, the development of …
[HTML][HTML] A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma
Background Improved usage of the repertoires of pancreatic ductal adenocarcinoma
(PDAC) profiles is crucially needed to guide the development of predictive and prognostic …
(PDAC) profiles is crucially needed to guide the development of predictive and prognostic …