Identification of novel genes associated with a poor prognosis in pancreatic ductal adenocarcinoma via a bioinformatics analysis

J Zhou, X Hui, Y Mao, L Fan - Bioscience Reports, 2019 - portlandpress.com
Pancreatic ductal adenocarcinoma (PDAC) is a class of the commonest malignant
carcinomas. The present study aimed to elucidate the potential biomarker and prognostic …

[HTML][HTML] Identifying MMP14 and COL12A1 as a potential combination of prognostic biomarkers in pancreatic ductal adenocarcinoma using integrated bioinformatics …

J Ding, Y Liu, Y Lai - PeerJ, 2020 - peerj.com
Background Pancreatic ductal adenocarcinoma (PDAC) is a fatal malignant neoplasm. It is
necessary to improve the understanding of the underlying molecular mechanisms and …

[HTML][HTML] Proteomic analyses identify prognostic biomarkers for pancreatic ductal adenocarcinoma

D Hu, D Ansari, K Pawłowski, Q Zhou, A Sasor… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Here we
show that shotgun and targeted protein sequencing can be used to identify potential …

[HTML][HTML] Identification of prognostic risk factors for pancreatic cancer using bioinformatics analysis

D Jin, Y Jiao, J Ji, W Jiang, W Ni, Y Wu, R Ni, C Lu… - PeerJ, 2020 - peerj.com
Background Pancreatic cancer is one of the most common malignant cancers worldwide.
Currently, the pathogenesis of pancreatic cancer remains unclear; thus, it is necessary to …

[HTML][HTML] Seven-gene signature on tumor microenvironment for predicting the prognosis of patients with pancreatic cancer

B Yang, J Xie, Z Li, D Su, L Lin, X Guo, Z Fu… - Gland …, 2021 - ncbi.nlm.nih.gov
Background The aim of the present study was to construct a novel gene signature on the
tumor microenvironment (TME) to predict the prognosis of patients with pancreatic ductal …

Morphological classification of pancreatic ductal adenocarcinoma that predicts molecular subtypes and correlates with clinical outcome

SN Kalimuthu, GW Wilson, RC Grant, M Seto… - Gut, 2020 - gut.bmj.com
Introduction Transcriptional analyses have identified several distinct molecular subtypes in
pancreatic ductal adenocarcinoma (PDAC) that have prognostic and potential therapeutic …

Bioinformatic analysis reveals pancreatic cancer molecular subtypes specific to the tumor and the microenvironment

TYS Le Large, M Mato Prado, J Krell… - Expert review of …, 2016 - Taylor & Francis
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease characterized by a dense
desmoplastic reaction surrounding malignant epithelial cells. Interaction between the …

Identification of critical pathways and potential key genes in poorly differentiated pancreatic adenocarcinoma

Y Lu, D Li, G Liu, E Xiao, S Mu, Y Pan, F Qin… - OncoTargets and …, 2021 - Taylor & Francis
Introduction The poorly differentiated pancreatic adenocarcinoma (PDAC) is an extremely
lethal neoplasm without effective biomarkers for early detection and prognosis prediction …

[HTML][HTML] Identification of key genes involved in pancreatic ductal adenocarcinoma with diabetes mellitus based on gene expression profiling analysis

W Zhou, Y Wang, H Gao, Y Jia, Y Xu… - Pathology and …, 2021 - por-journal.com
This study aimed to identify key genes involved in the progression of diabetic pancreatic
ductal adenocarcinoma (PDAC). Two gene expression datasets (GSE74629 and …

[HTML][HTML] RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer

Y Mao, J Shen, Y Lu, K Lin, H Wang, Y Li, P Chang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Gene expression microarrays have identified many tumor markers and therapeutic targets
for pancreatic ductal adenocarcinoma (PDAC). However, microarray profilings have limited …