[HTML][HTML] Adipose tissues as an ancestral immune organ: site-specific change in obesity
S Caspar-Bauguil, B Cousin, A Galinier, C Segafredo… - FEBS letters, 2005 - Elsevier
Close relationships have been demonstrated between adipose tissue and the
inflammatory/immune system. Furthermore, obesity is increasingly considered as a state of …
inflammatory/immune system. Furthermore, obesity is increasingly considered as a state of …
Emerging mechanisms of obesity-associated immune dysfunction
SR Shaikh, MA Beck, Y Alwarawrah… - Nature Reviews …, 2024 - nature.com
Obesity is associated with a wide range of complications, including type 2 diabetes mellitus,
cardiovascular disease, hypertension and nonalcoholic fatty liver disease. Obesity also …
cardiovascular disease, hypertension and nonalcoholic fatty liver disease. Obesity also …
Macrophages: gatekeepers of tissue integrity
Macrophages form a heterogeneous group of hematopoietic cells that reside in tissues,
where they are required to maintain organ integrity. Tissue macrophages contribute to tissue …
where they are required to maintain organ integrity. Tissue macrophages contribute to tissue …
[HTML][HTML] Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells
PA Louwe, L Badiola Gomez, H Webster… - Nature …, 2021 - nature.com
Inflammation generally leads to recruitment of monocyte-derived macrophages. What
regulates the fate of these cells and to what extent they can assume the identity and function …
regulates the fate of these cells and to what extent they can assume the identity and function …
The biology of serous cavity macrophages
CC Bain, SJ Jenkins - Cellular immunology, 2018 - Elsevier
For decades, it has been known that the serous cavities, which include the peritoneal,
pleural and pericardial cavities, harbour large numbers of macrophages. In particular, due to …
pleural and pericardial cavities, harbour large numbers of macrophages. In particular, due to …
Lipid-associated macrophages in the tumor-adipose microenvironment facilitate breast cancer progression
Z Liu, Z Gao, B Li, J Li, Y Ou, X Yu, Z Zhang… - …, 2022 - Taylor & Francis
The tumor-adipose microenvironment (TAME) is a universal microecosystem, that is
characterized by the dysfunction of lipid metabolism, such as excessive free fatty acids …
characterized by the dysfunction of lipid metabolism, such as excessive free fatty acids …
Adipose tissue macrophages and their polarization in health and obesity
L Catrysse, G van Loo - Cellular immunology, 2018 - Elsevier
Adipose tissue is a special tissue environment due to its high lipid content. Adipose tissue
macrophages (ATMs) help maintain adipose tissue homeostasis in steady state by clearing …
macrophages (ATMs) help maintain adipose tissue homeostasis in steady state by clearing …
Interactions between adipose tissue and the immune system in health and malnutrition
Adipose tissue provides the body with a storage depot of nutrients that is drained during
times of starvation and replenished when food sources are abundant. As such, it is the …
times of starvation and replenished when food sources are abundant. As such, it is the …
Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages
Macrophages reside in the body cavities where they maintain serosal homeostasis and
provide immune surveillance. Peritoneal macrophages are implicated in the etiology of …
provide immune surveillance. Peritoneal macrophages are implicated in the etiology of …