[HTML][HTML] Adipose tissues as an ancestral immune organ: site-specific change in obesity

S Caspar-Bauguil, B Cousin, A Galinier, C Segafredo… - FEBS letters, 2005 - Elsevier
Close relationships have been demonstrated between adipose tissue and the
inflammatory/immune system. Furthermore, obesity is increasingly considered as a state of …

Adipose tissue as an immunological organ

RW Grant, VD Dixit - Obesity, 2015 - Wiley Online Library
Objective This review will focus on the immunological aspects of adipose tissue and its
potential role in development of chronic inflammation that instigates obesity‐associated …

Emerging mechanisms of obesity-associated immune dysfunction

SR Shaikh, MA Beck, Y Alwarawrah… - Nature Reviews …, 2024 - nature.com
Obesity is associated with a wide range of complications, including type 2 diabetes mellitus,
cardiovascular disease, hypertension and nonalcoholic fatty liver disease. Obesity also …

Macrophages: gatekeepers of tissue integrity

Y Lavin, M Merad - Cancer immunology research, 2013 - AACR
Macrophages form a heterogeneous group of hematopoietic cells that reside in tissues,
where they are required to maintain organ integrity. Tissue macrophages contribute to tissue …

[HTML][HTML] Recruited macrophages that colonize the post-inflammatory peritoneal niche convert into functionally divergent resident cells

PA Louwe, L Badiola Gomez, H Webster… - Nature …, 2021 - nature.com
Inflammation generally leads to recruitment of monocyte-derived macrophages. What
regulates the fate of these cells and to what extent they can assume the identity and function …

The biology of serous cavity macrophages

CC Bain, SJ Jenkins - Cellular immunology, 2018 - Elsevier
For decades, it has been known that the serous cavities, which include the peritoneal,
pleural and pericardial cavities, harbour large numbers of macrophages. In particular, due to …

Lipid-associated macrophages in the tumor-adipose microenvironment facilitate breast cancer progression

Z Liu, Z Gao, B Li, J Li, Y Ou, X Yu, Z Zhang… - …, 2022 - Taylor & Francis
The tumor-adipose microenvironment (TAME) is a universal microecosystem, that is
characterized by the dysfunction of lipid metabolism, such as excessive free fatty acids …

Adipose tissue macrophages and their polarization in health and obesity

L Catrysse, G van Loo - Cellular immunology, 2018 - Elsevier
Adipose tissue is a special tissue environment due to its high lipid content. Adipose tissue
macrophages (ATMs) help maintain adipose tissue homeostasis in steady state by clearing …

Interactions between adipose tissue and the immune system in health and malnutrition

FM Wensveen, S Valentić, M Šestan… - Seminars in …, 2015 - Elsevier
Adipose tissue provides the body with a storage depot of nutrients that is drained during
times of starvation and replenished when food sources are abundant. As such, it is the …

Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

CC Bain, DA Gibson, NJ Steers, K Boufea… - Science …, 2020 - science.org
Macrophages reside in the body cavities where they maintain serosal homeostasis and
provide immune surveillance. Peritoneal macrophages are implicated in the etiology of …