The purpose of this study was to evaluate the effect of process (homogenization speed and
evaporation time) and formulation (aqueous/organic phase ratio, surfactant concentration …

Purpose. We successfully manufactured nanoparticles of biodegradable polymers for
controlled release of paclitaxel. TPGS (d-α-tocopheryl polyethylene glycol 1000 succinate) …

Paclitaxel is one of the best antineoplastic drugs found from nature in the past decades,
which has been found effective against a wide spectrum of cancers including ovarian …

This work evaluates the effects of paclitaxel loaded polymeric nanoparticles (NPs)
composed of poly (D, L-lactic-co-glycolic acid)(PLGA) with vitamin E TPGS as emulsifier for …

The purpose of this work was to develop Cremophor® EL-free nanoparticles (NPs) loaded
with Paclitaxel (PTX) in order to improve the drug iv pharmacokinetic profile and to evaluate …

The aim of the present work was to assess the merits of an actively targetable nanoparticles
(ATN), PEG-coated biodegradable polycyanoacrylate nanoparticles (PEG-nanoparticles) …

Polymeric nanoparticles (NPs) have great potential application in achieving targeted
delivery of anticancer drugs. Paclitaxel (PTX) loaded NPs were developed using …

Background Nanoparticles fabricated from the biodegradable and biocompatible polymer,
polylactic-co-glycolic acid (PLGA), are the most intensively investigated polymers for drug …

Paclitaxel (Taxol®) is one of the best antineoplastic drugs found from nature in the past
decades. Like many other anticancer drugs, there are difficulties in its clinical administration …

The aim of this study was to develop an alternative, more bio-available, better tolerated
paclitaxel nanosuspension (PTXNS) for intravenous injection in comparison with …