Novel biomarkers and therapeutic targets for melanoma

N Sabag, A Yakobson, M Retchkiman… - International Journal of …, 2022 - mdpi.com
Malignant melanoma is one of the most common cancers in the world. In the disease's early
stages, treatment involves surgery, in advanced stages however, treatment options were …

Molecular and immune biomarkers for cutaneous melanoma: current status and future prospects

L Pilla, A Alberti, P Di Mauro, M Gemelli, V Cogliati… - Cancers, 2020 - mdpi.com
Simple Summary The prognosis and treatment of metastatic melanoma have changed
substantially since the advent of target therapy and immune checkpoint inhibitors. Thus …

[HTML][HTML] Pathways and therapeutic targets in melanoma

E Shtivelman, MA Davies, P Hwu, J Yang, M Lotem… - Oncotarget, 2014 - ncbi.nlm.nih.gov
This review aims to summarize the current knowledge of molecular pathways and their
clinical relevance in melanoma. Metastatic melanoma was a grim diagnosis, but in recent …

Personalized medicine in malignant melanoma: towards patient tailored treatment

H Helgadottir, I Rocha Trocoli Drakensjö… - Frontiers in …, 2018 - frontiersin.org
Despite enormous international efforts, skin melanoma is still a major clinical challenge.
Melanoma takes a top place among the most common cancer types and it has one of the …

Future perspectives in melanoma research. Meeting report from the" Melanoma Research: a bridge Naples-USA. Naples, December 6 th-7 th 2010"

PA Ascierto, E De Maio, S Bertuzzi, G Palmieri… - Journal of Translational …, 2011 - Springer
Progress in understanding the molecular basis of melanoma has made possible the
identification of molecular targets with important implications in clinical practice. In fact, new …

Molecular Frontiers in Melanoma: Pathogenesis, Diagnosis, and Therapeutic Advances

HJ Kim, YH Kim - International Journal of Molecular Sciences, 2024 - mdpi.com
Melanoma, a highly aggressive skin cancer, is characterized by rapid progression and high
mortality. Recent advances in molecular pathogenesis have shed light on genetic and …

Melanoma from molecular pathways to clinical treatment: an up to date review

C Kosmidis, S Baka, K Sapalidis… - Journal of …, 2017 - jbiomed.com
Skin cancer is divided to melanoma and non-melanoma. Melanoma occurs due to
deregulation of melanocytes. Melanoma is frequent in Caucasian population. During the last …

Diagnostic and prognostic biomarkers in melanoma: current state of play

J Utikal, JC Becker, S Ugurel - Diagnostic and Prognostic Biomarkers and …, 2011 - Springer
Melanoma is the most deadly skin cancer. The incidence and mortality rates of this tumor
have been increasing over the last number of decades. Besides clinical and …

Established and emerging biomarkers in cutaneous malignant melanoma

S Verykiou, RA Ellis, PE Lovat - Healthcare, 2014 - mdpi.com
In an era of personalized medicine, disease specific biomarkers play an increasing role in
the stratification of high-risk patient groups. Cutaneous malignant melanoma is the most …

Biomarkers in melanoma: Lessons from translational medicine

EI Buchbinder, KT Flaherty - Trends in Cancer, 2016 - cell.com
The treatment landscape for advanced melanoma has been rapidly evolving. As new
therapies become available, there is a need for better biomarkers to detect disease, guide …