[PDF][PDF] In silico identification of novel drug targets in acinetobacter baumannii by subtractive genomic approach
Objective: Multiple drug resistance (MDR) in bacteria, particularly Gram-negative bacilli, has
significantly hindered the treatment of infections caused by these bacteria. This results in the …
significantly hindered the treatment of infections caused by these bacteria. This results in the …
Identification of putative non-host essential genes and novel drug targets against Acinetobacter baumannii by in silico comparative genome analysis
Acinetobacter baumannii, the gram-negative bacteria emerged as an extremely critical
pathogen causing nosocomial and different kinds of infections. A. baumannii exhibit …
pathogen causing nosocomial and different kinds of infections. A. baumannii exhibit …
Identification of novel non-homologous drug targets against Acinetobacter baumannii using subtractive genomics and comparative metabolic pathway analysis
Lack of effective antibiotics and the development of multidrug resistance in clinical isolates
of nosocomial pathogen Acinetobacter baumanni has necessitated the identification of novel …
of nosocomial pathogen Acinetobacter baumanni has necessitated the identification of novel …
In Silico Identification of Probable Drug and Vaccine Candidates Against Antibiotic-Resistant Acinetobacter baumannii
E Zadeh Hosseingholi, G Zarrini… - Microbial Drug …, 2020 - liebertpub.com
Acinetobacter baumannii is known as a Gram-negative bacterium that has become one of
the most important health problems due to antibiotic resistance. Today, numerous efforts are …
the most important health problems due to antibiotic resistance. Today, numerous efforts are …
Computer-Based Identification of Potential Druggable Targets in Multidrug-Resistant Acinetobacter baumannii: A Combined In Silico, In Vitro and In Vivo Study
The remarkable rise in antimicrobial resistance is alarming for Acinetobacter baumannii,
which necessitates effective strategies for the discovery of promising anti-acinetobacter …
which necessitates effective strategies for the discovery of promising anti-acinetobacter …
Genome-Wide Identification of Potential Drug Target in Enterobacteriaceae Family: A Homology-Based Method
M Hadizadeh, SN Tabatabaiepour… - Microbial Drug …, 2018 - liebertpub.com
The Enterobacteriaceae is a large family of Gram-negative, facultative anaerobic, non-spore
forming rod-shaped bacteria that includes harmless and pathogenic organisms. The …
forming rod-shaped bacteria that includes harmless and pathogenic organisms. The …
Identification and characterization of potential drug targets by subtractive genome analyses of methicillin resistant Staphylococcus aureus
R Uddin, K Saeed - Computational biology and chemistry, 2014 - Elsevier
Methicillin resistant Staphylococcus aureus (MRSA) causes serious infections in humans
and becomes resistant to a number of antibiotics. Due to the emergence of antibiotic …
and becomes resistant to a number of antibiotics. Due to the emergence of antibiotic …
Identification of Druggable Targets for Acinetobacter baumannii Via Subtractive Genomics and Plausible Inhibitors for MurA and MurB
N Kaur, M Khokhar, V Jain, PV Bharatam… - Applied biochemistry …, 2013 - Springer
Emergence of the multidrug-resistant pathogens has rendered the current therapies
ineffective thereby, resulting in the need for new drugs and drug targets. The accumulating …
ineffective thereby, resulting in the need for new drugs and drug targets. The accumulating …
In silico identification of putative drug targets from different metabolic pathways of Aeromonas hydrophila
V Sharma, P Gupta, A Dixit - In silico biology, 2008 - content.iospress.com
Aeromonas hydrophila is a major pathogen both of aquatic and terrestrial organisms,
including humans. Infection with A. hydrophila results in severe economic losses to the …
including humans. Infection with A. hydrophila results in severe economic losses to the …
In Silico Identification and Characterization of Drug Targets in Streptococcus pneumoniae ATCC 700669 (Serotype 23F) by Subtractive Genomics
T Duguma, H Dinka - BioMed Research International, 2024 - Wiley Online Library
Streptococcus pneumoniae (S. pneumoniae) is an important pathogen worldwide that
causes pneumococcal infections which are related to high rates of morbidity and mortality …
causes pneumococcal infections which are related to high rates of morbidity and mortality …
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