Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers
F Islam, Z Dehbia, M Zehravi, R Das… - Chemico-Biological …, 2023 - Elsevier
Cancer is the leading cause of mortality all over the world. Scientific investigation has
demonstrated that disruptions in the process of autophagy are frequently interrelated with …
demonstrated that disruptions in the process of autophagy are frequently interrelated with …
Indole alkaloid marine natural products: An established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other …
The marine environment produces natural products from a variety of structural classes
exhibiting activity against numerous disease targets. Historically marine natural products …
exhibiting activity against numerous disease targets. Historically marine natural products …
Marine-derived indole alkaloids and their biological and pharmacological activities
Novel secondary metabolites from marine macroorganisms and marine-derived
microorganisms have been intensively investigated in the last few decades. Several classes …
microorganisms have been intensively investigated in the last few decades. Several classes …
The current scenario of naturally occurring indole alkaloids with anticancer potential
J Song, B Zhang, M Li, J Zhang - Fitoterapia, 2023 - Elsevier
Naturally occurring indole alkaloids are ubiquitously present in nature and possess
extensive biological properties and structural diversity. Mechanistically, naturally occurring …
extensive biological properties and structural diversity. Mechanistically, naturally occurring …
Marine indole alkaloids
N Netz, T Opatz - Marine drugs, 2015 - mdpi.com
Marine indole alkaloids comprise a large and steadily growing group of secondary
metabolites. Their diverse biological activities make many compounds of this class attractive …
metabolites. Their diverse biological activities make many compounds of this class attractive …
[HTML][HTML] Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagy
ML Luo, W Huang, HP Zhu, C Peng, Q Zhao… - Biomedicine & …, 2022 - Elsevier
Cancer is a leading cause of death worldwide, and cancer development is often associated
with disturbances in the autophagy process. Autophagy is a catabolic process involved in …
with disturbances in the autophagy process. Autophagy is a catabolic process involved in …
Current Status of Indole-Derived Marine Natural Products: Synthetic Approaches and Therapeutic Applications
S Fernández, V Arnáiz, D Rufo, Y Arroyo - Marine Drugs, 2024 - mdpi.com
Indole is a versatile pharmacophore widely distributed in bioactive natural products. This
privileged scaffold has been found in a variety of molecules isolated from marine organisms …
privileged scaffold has been found in a variety of molecules isolated from marine organisms …
Molecular and biological investigation of isolated marine fungal metabolites as anticancer agents: a multi-target approach
Cancer is the leading cause of death globally, with an increasing number of cases being
annually reported. Nature-derived metabolites have been widely studied for their potential …
annually reported. Nature-derived metabolites have been widely studied for their potential …
Marine indole alkaloids—Isolation, structure and bioactivities
Y Hu, S Chen, F Yang, S Dong - Marine Drugs, 2021 - mdpi.com
Indole alkaloids are heterocyclic natural products with extensive pharmacological activities.
As an important source of lead compounds, many clinical drugs have been derived from …
As an important source of lead compounds, many clinical drugs have been derived from …
Alkaloids from marine invertebrates as important leads for anticancer drugs discovery and development
C Imperatore, A Aiello, F D'Aniello, M Senese… - Molecules, 2014 - mdpi.com
The present review describes research on novel natural antitumor alkaloids isolated from
marine invertebrates. The structure, origin, and confirmed cytotoxic activity of more than 130 …
marine invertebrates. The structure, origin, and confirmed cytotoxic activity of more than 130 …