[HTML][HTML] Genetic battle between Helicobacter pylori and humans. The mechanism underlying homologous recombination in bacteria, which can infect human cells

K Hanada, Y Yamaoka - Microbes and infection, 2014 - Elsevier
Helicobacter pylori is a gram-negative pathogenic bacterium that colonises the human
stomach. The chronic infection it causes results in peptic ulcers and gastric cancers. H. pylori …

Recombination and DNA Repair in Helicobacter pylori

MS Dorer, TH Sessler, NR Salama - Annual review of …, 2011 - annualreviews.org
All organisms have pathways that repair the genome, ensuring their survival and that of their
progeny. But these pathways also serve to diversify the genome, causing changes at the …

Host Adaptation and Immune Modulation Are Mediated by Homologous Recombination in Helicobacter pylori

K Robinson, MF Loughlin, R Potter… - The Journal of …, 2005 - academic.oup.com
Rearrangement of genomic DNA via homologous recombination provides an alternative
mechanism of gene regulation that is essential for successful colonization of the gastric …

The Remarkable Genetics of Helicobacter pylori

D Falush - Mbio, 2022 - Am Soc Microbiol
The Helicobacter pylori genome is more thoroughly mixed by homologous recombination
than by any other organism that has been investigated, leading to apparent “free …

[HTML][HTML] DNA Damage Triggers Genetic Exchange in Helicobacter pylori

MS Dorer, J Fero, NR Salama - PLoS pathogens, 2010 - journals.plos.org
Many organisms respond to DNA damage by inducing expression of DNA repair genes. We
find that the human stomach pathogen Helicobacter pylori instead induces transcription and …

Genetic dissection of Helicobacter pylori AddAB role in homologous recombination

S Marsin, A Lopes, A Mathieu, E Dizet… - FEMS microbiology …, 2010 - academic.oup.com
Helicobacter pylori infects the stomach of about half of the world's human population,
frequently causing chronic inflammation at the origin of several gastric pathologies. One of …

Mutation and recombination in Helicobacter pylori: mechanisms and role in generating strain diversity

C Kraft, S Suerbaum - International journal of medical microbiology, 2005 - Elsevier
The pathogenic bacterium Helicobacter pylori infects half of the human population and it is
one of the most genetically diverse bacterial species known. The unusual combination of …

Characterization of Helicobacter pylori factors that control transformation frequency and integration length during inter‐strain DNA recombination

O Humbert, MS Dorer, NR Salama - Molecular microbiology, 2011 - Wiley Online Library
Helicobacter pylori is a genetically diverse bacterial species, owing in part to its natural
competence for DNA uptake that facilitates recombination between strains. Inter‐strain DNA …

Emergence of recombinant strains of Helicobacter pylori during human infection

D Kersulyte, H Chalkauskas, DE Berg - Molecular microbiology, 1999 - Wiley Online Library
Genetic recombination can be important evolutionarily in speeding the adaptation of
organisms to new environments and in purging deleterious mutations. Here, we describe …

Evolution of Helicobacter pylori: the role of recombination

S Suerbaum, M Achtman - Trends in microbiology, 1999 - cell.com
Helicobacter pylori is one of the most common pathogenic bacteria infecting humans. It is
estimated that more than half of the human population is chronically colonized with this …