Introduction Trials to test disease-modifying treatments for frontotemporal dementia are
eagerly awaited and sensitive instruments to assess potential treatment effects are …

In genetic frontotemporal dementia, cross-sectional studies have identified profiles of
presymptomatic neuroanatomical loss for C9orf72 repeat expansion, MAPT, and GRN …

Introduction Frontotemporal dementia (FTD) is a common cause of early-onset dementia
with a significant genetic component, as underlined by the recent identification of repeat …

Frontotemporal lobar degeneration (FTLD) is a neurodegenerative disorder characterized
by behavioral changes, language abnormality, as well as executive function deficits and …

Presymptomatic carriers of GRN and C9orf72 mutations, the most frequent genetic causes of
frontotemporal lobar degeneration, represent the optimal target population for the …

Neurophysiological biomarkers were assessed using a transcranial magnetic stimulation
multiparadigm approach in 13 presymptomatic (n= 13 Granulin) and 14 symptomatic (n= 11 …

Background and Objectives To assess cortical, subcortical, and cerebellar gray matter (GM)
atrophy using MRI in patients with disorders of the frontotemporal lobar degeneration (FTLD) …

Background Current clinical rating scales in frontotemporal dementia (FTD) often do not
incorporate neuropsychiatric features and may therefore inadequately measure disease …

Introduction We performed 4-year follow-up neuropsychological assessment to investigate
cognitive decline and the prognostic abilities from presymptomatic to symptomatic familial …

Frontotemporal dementia (FTD) is a heterogeneous group of disorders causing
neurodegeneration within a network of areas centred on the frontal and temporal lobes …