Comparison of the effects of medical and surgical treatments in giant prolactinoma: a single-center experience

S Cander, O Oz Gul, E Eylemer, E Gullulu Boz… - Hormones, 2021 - Springer
Purpose Giant prolactinomas, which have extremely large sizes and high prolactin (PRL)
values, are rarely seen. Although medical therapy is effective, surgical treatment is more …

Management and outcomes of giant prolactinoma: a series of 71 patients

O ksana Hamidi, J Van Gompel, L Gruber, NE Kittah… - Endocrine Practice, 2019 - Elsevier
Objective: To describe outcomes of patients with giant prolactinoma (≥ 4 cm) and identify
predictors of therapeutic response. Methods: In this retrospective study, complete …

Giant prolactinomas, a detailed analysis of 196 adult cases

B Lisa, V Arno, DB Christophe, V Heyning Paul… - Pituitary, 2023 - Springer
Purpose Giant prolactinomas are a rare entity, representing approximately 5% of all
prolactinomas. A systematic review of 196 adult cases was performed. A comparison of the …

Giant prolactinomas: the therapeutic approach

AB Moraes, C Marques dos Santos Silva… - Clinical …, 2013 - Wiley Online Library
Background Giant prolactinomas are an unusual subset of macroprolactinomas and are
more commonly found in men. The goal of this review is to propose a giant prolactinoma …

Long-term outcome of multimodal therapy for giant prolactinomas

P Andujar-Plata, R Villar-Taibo, MD Ballesteros-Pomar… - Endocrine, 2017 - Springer
Giant prolactinomas are rare tumors characterized by their large size, compressive
symptoms, and extremely high prolactin secretion. The aim of this study is to describe our …

Giant prolactinomas: clinical manifestations and outcomes of 16 Arab cases

MH Almalki, B Buhary, S Alzahrani, F Alshahrani… - Pituitary, 2015 - Springer
Background The management of giant prolactinomas remains a major challenge, despite
dopamine agonists being the first line of treatment, owing to its efficacy to normalize …

Long-term Follow-up of 84 Patients With Giant Prolactinomas—A Swedish Nationwide Study

C Himonakos, P Burman, H Borg… - The Journal of …, 2023 - academic.oup.com
Purpose To describe the clinical presentation and treatment outcomes in a nationwide
cohort of patients with giant prolactinomas. Methods Register-based study of patients with …

Giant prolactinomas: are they really different from ordinary macroprolactinomas?

E Espinosa, E Sosa, V Mendoza, C Ramírez, V Melgar… - Endocrine, 2016 - Springer
Giant prolactinomas (gPRLomas) are rare tumors of the lactotroph defined by an unusually
large size (> 4 cm) and serum PRL levels> 1000 ng/mL. The purpose of this study is to …

Clinical features, therapeutic trends, and outcome of giant prolactinomas: a single-center experience over a 12-year period

MH Almalki, N Aljohani, S Alzahrani… - Clinical Medicine …, 2020 - journals.sagepub.com
Background: Management of giant prolactinomas presents a different challenge than the
management of traditional prolactinomas. Objective: The aim of this study was to report the …

Surgical management of giant prolactinomas: a descriptive study

MD Lundholm, D Yogi-Morren… - International Journal …, 2023 - Wiley Online Library
Introduction. Giant prolactinoma (GP) is a rare pituitary lactotropic cell tumor larger than 4 cm
in its widest dimension, and is less likely than a smaller prolactinoma to achieve prolactin …