Persistence versus Escape: Aspergillus terreus and Aspergillus fumigatus Employ Different Strategies during Interactions with Macrophages

S Slesiona, M Gressler, M Mihlan, C Zaehle… - PloS one, 2012 - journals.plos.org
Invasive bronchopulmonary aspergillosis (IBPA) is a life-threatening disease in
immunocompromised patients. Although Aspergillus terreus is frequently found in the …

Lung and gut microbiomes in pulmonary aspergillosis: Exploring adjunctive therapies to combat the disease

L Cai, P Gao, Z Wang, C Dai, Y Ning, M Ilkit… - Frontiers in …, 2022 - frontiersin.org
Species within the Aspergillus spp. cause a wide range of infections in humans, including
invasive pulmonary aspergillosis, chronic pulmonary aspergillosis, and allergic …

Coevolution of TH1, TH2, and TH17 Responses during Repeated Pulmonary Exposure to Aspergillus fumigatus Conidia

BJ Murdock, AB Shreiner, RA McDonald… - Infection and …, 2011 - Am Soc Microbiol
Aspergillus fumigatus, a ubiquitous airborne fungus, can cause invasive infection in
immunocompromised individuals but also triggers allergic bronchopulmonary aspergillosis …

Aspergillus and the Lung

I Janssens, BN Lambrecht… - Seminars in Respiratory …, 2024 - thieme-connect.com
The filamentous fungus Aspergillus causes a wide spectrum of diseases in the human lung,
with Aspergillus fumigatus being the most pathogenic and allergenic subspecies. The broad …

Hide, Keep Quiet, and Keep Low: Properties That Make Aspergillus fumigatus a Successful Lung Pathogen

N Escobar, SR Ordonez, HAB Wösten… - Frontiers in …, 2016 - frontiersin.org
Representatives of the genus Aspergillus are opportunistic fungal pathogens. Their conidia
can reach the alveoli by inhalation and can give rise to infections in immunocompromised …

Evolution of the immune response to chronic airway colonization with Aspergillus fumigatus hyphae

M Urb, BD Snarr, G Wojewodka, M Lehoux… - Infection and …, 2015 - Am Soc Microbiol
Airway colonization by the mold Aspergillus fumigatus is common in patients with underlying
lung disease and is associated with chronic airway inflammation. Studies probing the …

Heterogeneity among isolates reveals that fitness in low oxygen correlates with Aspergillus fumigatus virulence

CH Kowalski, SR Beattie, KK Fuller, EA McGurk… - MBio, 2016 - Am Soc Microbiol
Previous work has shown that environmental and clinical isolates of Aspergillus fumigatus
represent a diverse population that occupies a variety of niches, has extensive genetic …

Pulmonary aspergillosis: an evolving challenge for diagnosis and treatment

A Russo, G Tiseo, M Falcone, F Menichetti - Infectious diseases and …, 2020 - Springer
Aspergillus is a mold that may lead to different clinical pictures, from allergic to invasive
disease, depending on the patient's immune status and structural lung diseases. Chronic …

Interleukin 1α is critical for resistance against highly virulent Aspergillus fumigatus isolates

AK Caffrey-Carr, CH Kowalski, SR Beattie… - Infection and …, 2017 - Am Soc Microbiol
Heterogeneity among Aspergillus fumigatus isolates results in unique virulence potential
and inflammatory responses. How these isolates drive specific immune responses and how …

Inflammatory cells and airway defense against Aspergillus fumigatus

HF Kauffman, JFC Tomee - Immunology and allergy clinics of North …, 1998 - Elsevier
Aspergillus fumigatus is known as a cause of multiple airway diseases that range from
harmless saprophytic colonization (presence of the fungus in sputum of healthy individuals) …