Amiodarone is an antiarrhythmic agent with high iodine content. Ten patients treated with
amiodarone developed thyrotoxicosis. I 131 uptakes were negligible, and TT 3 levels low in …

Of a population of 400 patients treated with amiodarone, 97 underwent thyroid function
evaluation. Of these, 20 patients proved to be thyrotoxic and 16 hypothyroid. In thyrotoxic …

Amiodarone is a potent antiarrhythmic drug associated with thyroid dysfunction. Its high
iodine content causes inhibition of 5'-deiodinase activity. Most patients remain euthyroid …

Amiodarone-induced thyrotoxicosis: a difficult diagnostic and therapeutic challenge* Page 1
Clinical Endocrinology (2002) 56, 23–24 © 2002 Blackwell Science Ltd 23 Blackwell Science …

Amiodarone is a potent new antiarrhythmic drug that has multiple effects on thyroid function,
including inhibition of extrathyroidal triiodothyronine production and rarely, iodine-induced …

Although amiodarone is regarded as a highly effective anti-arrhythmic agent, its use may
lead to alterations in thyroid gland function and/or thyroid hormone metabolism, partly …

Amiodarone has been reported as an anti-anginal drug in 19h7 [11 and as an anti-
arrhythmic drug in 1969 [2]. Thyroid side-effects (hypothyroidism and thyrotoxicosis) were …

Both hyperthyroidism and hypothyroidism have been noted to occur in some patients treated
with amiodarone for cardiac arrhythmias. To determine the frequency of the development of …

Amiodarone, an iodinated benzofuran derivative, has electrophysiologic effects on cardiac
muscle akin to those of hypothyroidism. It is possible that the drug exerts its salutary effect, at …

The incidence of amiodarone-induced thyrotoxicosis remains unclear, partly due to the
difficulties encountered in making a firm diagnosis based on thyroid hormone levels …