Adaptations of a deep sea scavenger: high ammonia tolerance and active NH4+ excretion by the Pacific hagfish (Eptatretus stoutii)

AM Clifford, GG Goss, MP Wilkie - … and Physiology Part A: Molecular & …, 2015 - Elsevier
Abstract The Pacific hagfish (Eptatretus stoutii) has an exceptional ability to both withstand
and recover from exposure to high external ammonia (HEA). This tolerance is likely due to …

Dining on the dead in the deep: Active NH4+ excretion via Na+/H+(NH4+) exchange in the highly ammonia tolerant Pacific hagfish, Eptatretus stoutii

AM Clifford, MP Wilkie, SL Edwards… - Acta …, 2022 - Wiley Online Library
Aim Pacific hagfish are exceptionally tolerant to high environmental ammonia (HEA). Here,
we elucidated a cellular mechanism that enables hagfish to actively excrete ammonia …

Flexible ammonia handling strategies using both cutaneous and branchial epithelia in the highly ammonia-tolerant Pacific hagfish

AM Clifford, AM Weinrauch… - American Journal …, 2017 - journals.physiology.org
Hagfish consume carrion, potentially exposing them to hypoxia, hypercapnia, and high
environmental ammonia (HEA). We investigated branchial and cutaneous ammonia …

Ammonia toxicity, tolerance, and excretion

YK Ip, SF Chew, DJ Randall - Fish physiology, 2001 - Elsevier
Ammonia is an unusual toxicant in that it is produced by, as well as being poisonous to,
animals. In aqueous solution ammonia has two species, NH 3 and NH 4+, total ammonia is …

Physiological and molecular responses of the spiny dogfish shark (Squalus acanthias) to high environmental ammonia: scavenging for nitrogen

CM Nawata, PJ Walsh… - Journal of Experimental …, 2015 - journals.biologists.com
In teleosts, a branchial metabolon links ammonia excretion to Na+ uptake via Rh
glycoproteins and other transporters. Ureotelic elasmobranchs are thought to have low …

Strategies for Surviving High Concentrations of Environmental Ammonia in the Swamp Eel Monopterus albus

YK Ip, ASL Tay, KH Lee… - … and Biochemical Zoology, 2004 - journals.uchicago.edu
The swamp eel Monopterus albus lives in muddy ponds, swamps, canals, and rice fields in
the tropics. It encounters high concentrations of environmental ammonia (HEA) during dry …

The swamp eel Monopterus albus reduces endogenous ammonia production and detoxifies ammonia to glutamine during 144 h of aerial exposure

ASL Tay, SF Chew, YK Ip - Journal of experimental biology, 2003 - journals.biologists.com
The swamp eel Monopterus albus inhabits muddy ponds, swamps, canals and rice fields,
where it can burrow within the moist earth during the dry summer season, thus surviving for …

The mudskippers Periophthalmodon schlosseri and Boleophthalmus boddaerti can tolerate environmental NH3 concentrations of 446 and 36µM, respectively

KW Peng, SF Chew, CB Lim, SSL Kuah… - Fish Physiology and …, 1998 - Springer
The aim of this study was to elucidate if the mudskipper Periophthalmodon schlosseri, in
relation to its capability to survive on land, has acquired a greater capacity to detoxify …

Ammonia and Acid-Base Balance During High Ammonia Exposure in a Marine Teleost (Myoxocephalus Octodecimspinosus)

JB Claiborne, DH Evans - Journal of experimental biology, 1988 - journals.biologists.com
For the first time in a marine teleost (the long-horned sculpin; Myoxocephalus
octodecimspinosus), the maintenance of blood pH,,[HCO3−] and the net movements of …

Feeding through your gills and turning a toxicant into a resource: how the dogfish shark scavenges ammonia from its environment

CM Wood, M Giacomin - Journal of Experimental Biology, 2016 - journals.biologists.com
Nitrogen (N) appears to be a limiting dietary resource for elasmobranchs, required not only
for protein growth but also for urea-based osmoregulation. Building on recent evidence that …