Abstract Liver-expressed chemokine (LEC)/CCL16 is a human CC chemokine selectively
expressed in the liver. Here, we investigated its receptor usage by calcium mobilization and …

The infiltration of various immune cell populations, including monocytes/macrophages,
natural killer (NK), NKT cells and T cells, is a central pathogenic feature following acute-and …

Hepatocellular carcinoma, a deadly disease, commonly arises in the setting of chronic
inflammation. CC motif chemokine ligand 2 (CCL2/MCP1), a chemokine that recruits CCR2 …

Chemokines are small molecular weight proteins primarily known to drive migration of
immune cell populations. In both acute and chronic liver injury, hepatic chemokine …

Objective Hepatocellular carcinoma (HCC) is an aggressive malignancy with limited
effective treatment options. An alternative strategy is to target cells, such as tumour …

Human hepatocellular carcinoma (HCC) is an inflammation‐induced cancer, which is the
third‐leading cause of cancer mortality worldwide. We investigated the role of the …

Hepatitis C imposes a significant burden on global healthcare. Chronic infection is
associated with progressive inflammation of the liver which typically manifests in cirrhosis …

We previously observed that a chemokine, macrophage inflammatory protein‐1 α/CCL3,
and its receptor, CCR1, were aberrantly expressed in human hepatocellular carcinoma …

Background Chemokines contribute to the pathogenesis of autoimmune hepatitis by
directing the migration and positioning of inflammatory and immune cells within the liver …

Hepatoma cell lines can produce a massive amount of chemokines in response to various
stimuli including hepatitis viruses and their products. However, it remains elusive on the …