Genomic landscape of young ATLL patients identifies frequent targetable CD28 fusions
N Yoshida, K Shigemori, N Donaldson… - Blood, The Journal …, 2020 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATLL) in Japan presents at a median age of 70 years and
only 5% of patients are< 50 years of age. We conducted RNA and targeted DNA sequencing …
only 5% of patients are< 50 years of age. We conducted RNA and targeted DNA sequencing …
Clinical applications of genomic alterations in ATLL: predictive markers and therapeutic targets
N Yoshida, H Miyoshi, K Ohshima - Cancers, 2021 - mdpi.com
Simple Summary In this review paper, we aim to summarize recent findings of genomic
alterations found in adult T-cell leukemia/lymphoma (ATLL), which is an incurable disease …
alterations found in adult T-cell leukemia/lymphoma (ATLL), which is an incurable disease …
Prognostic implication of CTLA-4, PD-1, and PD-L1 expression in aggressive adult T-cell leukemia–lymphoma
The prognosis of patients with aggressive adult T cell leukemia–lymphoma (ATLL) is dismal
even with intensive chemotherapy. Allogeneic hematopoietic stem cell transplantation …
even with intensive chemotherapy. Allogeneic hematopoietic stem cell transplantation …
Comprehensive immunohistochemical analysis of immune checkpoint molecules in adult T cell leukemia/lymphoma
M Takeuchi, H Miyoshi, K Nakashima, K Kawamoto… - Annals of …, 2020 - Springer
Acute or lymphomatous type adult T cell leukemia/lymphoma (ATLL) is an aggressive
hematopoietic malignancy with poor prognosis. We previously reported that programmed …
hematopoietic malignancy with poor prognosis. We previously reported that programmed …
Loss of Foxp3 Is Associated With CD30 Expression in the Anaplastic Large Cell Subtype of Adult T-cell Leukemia/Lymphoma (ATLL) in US/Caribbean Patients …
J Yao, SRS Gottesman, G Ayalew… - The American Journal …, 2013 - journals.lww.com
Adult T-cell leukemia/lymphoma (ATLL) is caused by the HTLV-1 virus, endemic to Japan
and the Caribbean, and is likely derived from cells with the T-regulatory phenotype. The …
and the Caribbean, and is likely derived from cells with the T-regulatory phenotype. The …
North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies
Adult T-cell leukemia lymphoma (ATLL) is a rare T cell neoplasm that is endemic in
Japanese, Caribbean, and Latin American populations. Most North American ATLL patients …
Japanese, Caribbean, and Latin American populations. Most North American ATLL patients …
Molecular pathology of adult T-cell leukemia/lymphoma
K Ohshima - Oncology, 2015 - karger.com
Adult T-cell leukemia/lymphoma (ATLL) is a peripheral T-cell neoplasm of highly
pleomorphic lymphoid cells. ATLL is usually widely disseminated, and it is caused by human …
pleomorphic lymphoid cells. ATLL is usually widely disseminated, and it is caused by human …
Genetic alterations in adult T‐cell leukemia/lymphoma
Adult T‐cell leukemia/lymphoma (ATL) is a peripheral T‐cell neoplasm with a dismal
prognosis. It is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. A long …
prognosis. It is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. A long …
Integrated molecular analysis of adult T cell leukemia/lymphoma
K Kataoka, Y Nagata, A Kitanaka, Y Shiraishi… - Nature …, 2015 - nature.com
Adult T cell leukemia/lymphoma (ATL) is a peripheral T cell neoplasm of largely unknown
genetic basis, associated with human T cell leukemia virus type-1 (HTLV-1) infection. Here …
genetic basis, associated with human T cell leukemia virus type-1 (HTLV-1) infection. Here …
Differential CD30 expression in adult T-cell leukemia-lymphoma subtypes
G Campuzano-Zuluaga, A Pimentel… - Retrovirology, 2014 - Springer
Adult T-cell leukemia-lymphoma (ATLL) is caused by HTLV-I, and is a disease with dismal
prognosis urging new therapies. Brentuximab vedotin (SGN-35) is an anti-CD30 monoclonal …
prognosis urging new therapies. Brentuximab vedotin (SGN-35) is an anti-CD30 monoclonal …