Background. The study compares urine recirculation (URC) to urine replacement (UR) with
Ringer's lactate in a porcine normothermic kidney machine perfusion (NMP) model using a …

We describe a proteomics analysis to determine the molecular differences between
normothermically perfused (normothermic machine perfusion, NMP) human kidneys with …

Transportable normothermic kidney perfusion for 24 hours or longer could enable viability
assessment of marginal grafts, increased organ use, and improved transplant logistics …

Kidney transplantation has become a well-established treatment option for patients with end-
stage renal failure. The persisting organ shortage remains a serious problem. Therefore, the …

Normothermic machine perfusion (NMP) of donor kidneys provides the opportunity for
improved graft preservation and objective pre-transplant ex-vivo organ assessment …

End-stage renal disease (ESRD) is a major global health burden. It is projected that 5.4
million people will receive renal replacement therapy (RRT) by 2030 and up to …

Background Hypothermic kidney storage causes preservation injury and is poorly tolerated
by renal grafts. We investigated whether static cold storage (SCS) can be safely replaced …

Background The ongoing supply‐demand gap with respect to donor kidneys for
transplantation necessitates the increased use of higher kidney donor profile index and/or …

Background. Normothermic ex vivo kidney perfusion (NEVKP) has shown promising results
for preservation, assessment, and reconditioning of kidney allografts in preclinical studies …

Purpose Ex vivo perfusion of marginal kidney grafts offers the chance to expand the donor
pool, but there is no current clinical standard for the prolonged warm perfusion of renal …