Graphene oxide‐copper Nanocomposite‐coated porous CaP scaffold for vascularized bone regeneration via activation of Hif‐1α

W Zhang, Q Chang, L Xu, G Li, G Yang… - Advanced …, 2016 - Wiley Online Library
Graphene has been studied for its in vitro osteoinductive capacity. However, the in vivo bone
repair effects of graphene‐based scaffolds remain unknown. The aqueous soluble …

[HTML][HTML] Enhanced osteogenesis by reduced graphene oxide/hydroxyapatite nanocomposites

JH Lee, YC Shin, SM Lee, OS Jin, SH Kang… - Scientific reports, 2015 - nature.com
Recently, graphene-based nanomaterials, in the form of two dimensional substrates or three
dimensional foams, have attracted considerable attention as bioactive scaffolds to promote …

[HTML][HTML] Biomimetic reduced graphene oxide coated collagen scaffold for in situ bone regeneration

S Bahrami, N Baheiraei, M Shahrezaee - Scientific Reports, 2021 - nature.com
A variety of bone-related diseases and injures and limitations of traditional regeneration
methods require new tissue substitutes. Tissue engineering and regeneration combined …

Collagen functionalized with graphene oxide enhanced biomimetic mineralization and in situ bone defect repair

C Zhou, S Liu, J Li, K Guo, Q Yuan… - … applied materials & …, 2018 - ACS Publications
Biomimetic mineralization using simulated body fluid (SBF) can form a bonelike apatite (Ap)
on the natural polymers and enhance osteoconductivity and biocompatibility, and reduce …

Graphene nanoparticles as osteoinductive and osteoconductive platform for stem cell and bone regeneration

H Elkhenany, S Bourdo, S Hecht, R Donnell… - … , Biology and Medicine, 2017 - Elsevier
The potential of graphene-based nanoparticles (GNPs) has recently gained significant
attention in biomedicine, especially in tissue engineering. In this study, we investigated the …

Reduced graphene oxide-coated hydroxyapatite composites stimulate spontaneous osteogenic differentiation of human mesenchymal stem cells

JH Lee, YC Shin, OS Jin, SH Kang, YS Hwang, JC Park… - Nanoscale, 2015 - pubs.rsc.org
Human mesenchymal stem cells (hMSCs) have great potential as cell sources for bone
tissue engineering and regeneration, but the control and induction of their specific …

Osteoinductive and antimicrobial mechanisms of graphene‐based materials for enhancing bone tissue engineering

M Wu, L Zou, L Jiang, Z Zhao… - Journal of Tissue …, 2021 - Wiley Online Library
Graphene‐based materials (GMs) have great application prospects in bone tissue
engineering due to their osteoinductive ability and antimicrobial activity. GMs induce …

Fibrin hydrogel incorporated with graphene oxide functionalized nanocomposite scaffolds for bone repair—In vitro and in vivo study

S Pathmanapan, P Periyathambi… - … , Biology and Medicine, 2020 - Elsevier
Conventional bone repair therapies like the autologous and allogenic bone grafts have
failed to meet challenges in bone reconstruction along with complications. Tissue …

Graphene-oxide-modified β-tricalcium phosphate bioceramics stimulate in vitro and in vivo osteogenesis

C Wu, L Xia, P Han, M Xu, B Fang, J Wang, J Chang… - Carbon, 2015 - Elsevier
Graphene oxide (GO) has attracted much interest for applications in bone tissue
engineering; however, until now, the interaction between GO and stem cells, and the in vivo …

Functionalized graphene nanoparticles induce human mesenchymal stem cells to express distinct extracellular matrix proteins mediating osteogenesis

SD Newby, T Masi, CD Griffin, WJ King… - International journal …, 2020 - Taylor & Francis
Purpose The extracellular matrix (ECM) labyrinthine network secreted by mesenchymal
stem cells (MSCs) provides a microenvironment that enhances cell adherence, proliferation …