Purpose The proto-oncogene MYCN is considered a transcription factor involved in the
regulation of neuroblastoma (NB) cell biology. Since minimally invasive-surgery represents …

Introduction CO 2 pneumoperitoneum can influence the biological behavior of
neuroblastoma (NB). Angiogenesis and genetic features are responsible for malignant …

The ablative role of minimally invasive surgery (MIS) in neuroblastoma (NB) is still
controversial due to the possible CO₂ pneumoperitoneum side-effects on tumor …

Purpose: It has been reported that CO 2 gas, used to establish a pneumoperitoneum during
laparoscopy, affects the behavior of tumor cells. The proto-oncogenes c-myc and HMGB-1 …

Minimally invasive surgery (MIS) for cancer patients has become widely accepted in general
surgery, however, it has not completely replaced the standard open operative procedures in …

Purpose We evaluated in vitro the role of CO 2-induced oxidative stress on the expression of
proteins involved in cell-cycle regulation of neuroblastoma cells. Methods SH-SY5Y cells …

Objective This study aims to investigate the impacts of CO 2 pneumoperitoneum on the
growth of ovarian cancer in nude mice and the expression of tumor metastasis suppressor …

BACKGROUND: The expression of caspase-8, a cysteine protease that is crucial for the
apoptotic cascade, is absent in a high percentage of neuroblastomas, the most frequent …

BACKGROUND: Neuroblastoma is the most common pediatric solid extracranial
malignancy. Increased expression of MYCN, a member of Myc family, is associated with a …

Purpose Several oxygen-dependent factors, eg, CAIX (carbonic anhydrase IX) or
phosphoglycerate kinase 1 (PGK1) interacting with the CXCR4/SDF1 axis (chemokine …