Influence of structure of human, rat, and bovine serum albumins on binding properties of photoactive drug hypericin

J Hritz, S Kascakova, J Ulicny… - … : Original Research on …, 2002 - Wiley Online Library
Fluorescence binding measurements and molecular modeling were employed to study the
interaction of hypericin (Hyp) with human (HSA), rat (RSA), and bovine (BSA) serum …

Interaction of Hypericin with Serum Albumins: Surface‐enhanced Raman Spectroscopy, Resonance Raman Spectroscopy and Molecular Modeling Study¶

P Miskovsky, J Hritz, S Sanchez‐Cortes… - Photochemistry and …, 2001 - Wiley Online Library
Surface‐enhanced Raman spectroscopy, resonance Raman spectroscopy and molecular
modeling were employed to study the interaction of hypericin (Hyp) with human (HSA), rat …

Photophysics of hypericin and hypocrellin A in complex with subcellular components: interactions with human serum albumin

K Das, AV Smirnov, J Wen, P Miskovsky… - Photochemistry and …, 1999 - Wiley Online Library
Time‐resolved fluorescence and absorption measurements are performed on hypericin
complexed with human serum albumin, HSA (1: 4, 1: 1 and∼ 5: 1 hypericin: HSA …

Fluorescence Study on the Interaction Between Hypericin and Lens Protein “α‐Crystallin”

T Youssef - Photochemistry and photobiology, 2009 - Wiley Online Library
Hypericin has been reported as a potent photosensitizing agent exhibiting antiviral,
antibacterial, antineoplastic activities. Although its photophysics and mode of action are …

Spectroscopy studies of interaction hypericin with an anti-cancer therapy drug doxorubicin

M Pietrzak, M Szabelski, G Wołąkiewicz… - Biophysical …, 2022 - Elsevier
The presented study was designed to estimate the ability of hypericin to interact with the
anticancer drug doxorubicin. The hetero-association of hypericin and doxorubicin was …

How to make hypericin water-soluble

A Kubin, HG Loew, U Burner, G Jessner… - Die Pharmazie-An …, 2008 - ingentaconnect.com
Hypericin, isolated from Hypericum perforatum, is an effective photodynamic substance as
demonstrated by various studies. Practical forms of applications of hypericin solutions for …

Antiretrovirally active drug hypericin binds the IIA subdomain of human serum albumin: resonance Raman and surface-enhanced Raman spectroscopy study

P Miškovský, D Jancura… - Journal of the …, 1998 - ACS Publications
Resonance Raman and surface-enhanced Raman spectroscopy were employed to study
the interaction of hypericin with human serum albumin. The identification of the binding …

Kinetics of incorporation/redistribution of photosensitizer hypericin to/from high-density lipoproteins

J Joniova, L Buriankova, D Buzova, P Miskovsky… - International journal of …, 2014 - Elsevier
By means of fluorescence spectroscopy we have studied the kinetics of interaction of a
photosensitizer hypericin (Hyp) with high-density lipoproteins (HDL). Hyp is incorporated …

Photosensitization of aqueous model systems by hypericin

V Senthil, JW Longworth, CA Ghiron… - Biochimica et Biophysica …, 1992 - Elsevier
Absorption and fluorescence measurements of purified hypericin (HY) were made in various
media. Photosensitization of two aqueous systems was investigated: released red blood cell …

Spectroscopic Study of Visible‐light Effects on Hypericin‐lens Proteins Systems†¶

A Sgarbossa, F Lenci - Photochemistry and Photobiology, 2001 - Wiley Online Library
Molecular interactions between hypericin and α‐, β‐and γ‐crystallin proteins have been
studied by means of absorption and steady‐state fluorescence spectroscopy, aiming to …