International ring trial of a high resolution targeted metabolomics and lipidomics platform for serum and plasma analysis
JW Thompson, KJ Adams, J Adamski, Y Asad… - Analytical …, 2019 - ACS Publications
A challenge facing metabolomics in the analysis of large human cohorts is the cross-
laboratory comparability of quantitative metabolomics measurements. In this study, 14 …
laboratory comparability of quantitative metabolomics measurements. In this study, 14 …
Metabolite identification and quantitation in LC-MS/MS-based metabolomics
Metabolomics aims at detection and quantitation of all metabolites in biological samples.
The presence of metabolites with a wide variety of physicochemical properties and different …
The presence of metabolites with a wide variety of physicochemical properties and different …
Liquid chromatography–mass spectrometry based global metabolite profiling: a review
Untargeted, global metabolite profiling (often described as metabonomics or metabolomics)
represents an expanding research topic and is, potentially, a major pillar for systems biology …
represents an expanding research topic and is, potentially, a major pillar for systems biology …
Development and quantitative evaluation of a high-resolution metabolomics technology
Recent advances in mass spectrometry have allowed for unprecedented characterization of
human metabolism and its contribution to disease. Despite these advances, limitations in …
human metabolism and its contribution to disease. Despite these advances, limitations in …
Analytical strategies for LC–MS-based targeted metabolomics
Recent advances in mass spectrometry are enabling improved analysis of endogenous
metabolites. Here we discuss several issues relevant to developing liquid chromatography …
metabolites. Here we discuss several issues relevant to developing liquid chromatography …
metaMS: An open-source pipeline for GC–MS-based untargeted metabolomics
Untargeted metabolomics are rapidly becoming an important tool for studying complex
biological samples. Gas chromatography–mass spectrometry (GC–MS) is the most widely …
biological samples. Gas chromatography–mass spectrometry (GC–MS) is the most widely …
MetaboliteDetector: comprehensive analysis tool for targeted and nontargeted GC/MS based metabolome analysis
We have developed a new software, MetaboliteDetector, for the efficient and automatic
analysis of GC/MS-based metabolomics data. Starting with raw MS data, the program …
analysis of GC/MS-based metabolomics data. Starting with raw MS data, the program …
Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review
The metabolome is the set of small molecular mass organic compounds found in a given
biological media. It includes all organic substances naturally occurring from the metabolism …
biological media. It includes all organic substances naturally occurring from the metabolism …
Metabolomics technologies and metabolite identification
Metabolomics studies rely on the analysis of the multitude of small molecules (metabolites)
present in a biological system. Most commonly, metabolomics is heavily supported by mass …
present in a biological system. Most commonly, metabolomics is heavily supported by mass …
A metabolite array technology for precision medicine
The application of metabolomics in translational research suffers from several technological
bottlenecks, such as data reproducibility issues and the lack of standardization of sample …
bottlenecks, such as data reproducibility issues and the lack of standardization of sample …