Metabolomics is the untargeted measurement of the metabolome, which is composed of the
complement of small molecules detected in a biological sample. As such, metabolomic …

The field of metabolomics has witnessed an exponential growth in the last decade driven by
important applications spanning a wide range of areas in the basic and life sciences and …

Advances in mass spectrometry (MS) and data processing have led to discoveries in
regulation of cellular metabolism by using metabolomics and lipidomics approaches. 1, 2 …

We compared the performance of gas chromatography time-of-flight mass spectrometry (GC-
MS) and comprehensive two-dimensional gas chromatography mass spectrometry (GC× GC …

Background Non-targeted metabolomics based on mass spectrometry enables high-
throughput profiling of the metabolites in a biological sample. The large amount of data …

Metabolomics generates a profile of small molecules that are derived from cellular
metabolism and can directly reflect the outcome of complex networks of biochemical …

Large-scale proteomic and metabolomic technologies are increasingly gaining attention for
their use in the diagnosis of human disease. In order to ensure the statistical power of …

In order to perform metabonomic investigations, it is necessary to generate comprehensive
“global” metabolite profiles from complex samples, such as biofluids and tissues/tissue …

Metabolomics, in particular gas chromatography–mass spectrometry (GC–MS) based
metabolite profiling of biological extracts, is rapidly becoming one of the cornerstones of …

Background Standardization of analytical approaches and reporting methods via community-
wide collaboration can work synergistically with web-tool development to result in rapid …