[HTML][HTML] Long noncoding RNA RP11-838N2. 4 enhances the cytotoxic effects of temozolomide by inhibiting the functions of miR-10a in glioblastoma cell lines

Y Liu, N Xu, B Liu, Y Huang, H Zeng, Z Yang, Z He… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Resistance to temolozomide (TMZ), the standard chemotherapy agent for treating
glioblastomas (GBM), is a major clinical problem for patients with GBM. Recently, long …

Long noncoding RNA AC003092. 1 promotes temozolomide chemosensitivity through miR-195/TFPI-2 signaling modulation in glioblastoma

N Xu, B Liu, C Lian, DM Doycheva, Z Fu, Y Liu… - Cell death & …, 2018 - nature.com
Temozolomide (TMZ) and radiation therapy combination for glioblastoma (GB) patients has
been considered as the most effective therapy after surgical procedure. However, the overall …

Long noncoding RNA KCNQ1OT1 confers gliomas resistance to temozolomide and enhances cell growth by retrieving PIM1 from miR-761

W Wang, S Han, W Gao, Y Feng, K Li, D Wu - Cellular and Molecular …, 2022 - Springer
Many studies have found that the dysregulation of long noncoding RNA (lncRNA)
contributed to cancer initiation, progression, and recurrence via multiple signaling pathways …

Long intergenic noncoding RNA 00021 promotes glioblastoma temozolomide resistance by epigenetically silencing p21 through Notch pathway

S Zhang, S Guo, C Liang, M Lian - IUBMB life, 2020 - Wiley Online Library
Increasing findings are suggesting the vital roles of long noncoding RNAs (lncRNAs) in the
glioblastoma tumorigenesis. However, whether the novel lncRNA LINC00021 modulates …

lncRNA XLOC013218 promotes cell proliferation and TMZ resistance by targeting the PIK3R2‐mediated PI3K/AKT pathway in glioma

J Zhou, N Xu, B Liu, C Wang, Z He, C Lenahan… - Cancer …, 2022 - Wiley Online Library
The discovery of long noncoding RNAs (lncRNAs) has improved the understanding of
development and progression in various cancer subtypes. However, the role of lncRNAs in …

DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma

C Lu, Y Wei, X Wang, Z Zhang, J Yin, W Li, L Chen… - Molecular cancer, 2020 - Springer
Background Accumulating evidence shows that long noncoding RNAs (lncRNAs) are
important regulator molecules involved in diverse biological processes. Acquired drug …

Silencing lncRNA LINC01410 suppresses cell viability yet promotes apoptosis and sensitivity to temozolomide in glioblastoma cells by inactivating PTEN/AKT …

T Fu, Y Yang, Z Mu, R Sun, X Li… - Immunopharmacology …, 2021 - Taylor & Francis
Abstract Background Long non-coding RNAs (LncRNAs) are involved in glioblastoma
(GBM), but the role of long intergenic non-protein coding RNA 01410 (lncRNA LINC01410) …

LINC00511 facilitates Temozolomide resistance of glioblastoma cells via sponging miR‐126‐5p and activating Wnt/β‐catenin signaling

Y Lu, M Tian, J Liu, K Wang - Journal of Biochemical and …, 2021 - Wiley Online Library
Temozolomide (TMZ) is the first‐line chemotherapy drug for glioblastoma (GBM) but
acquired TMZ resistance is frequently observed. Thus, a TMZ resistant GBM cell line U87‐R …

Regulation of temozolomide resistance via lncRNAs: Clinical and biological properties of lncRNAs in gliomas

S Li, X Xie, F Peng, J Du… - … Journal of Oncology, 2022 - spandidos-publications.com
Gliomas are a primary types of intracranial malignancies and are characterized by a poor
prognosis due to aggressive recurrence profiles. Temozolomide (TMZ) is an auxiliary …

MicroRNA-195 reverses the resistance to temozolomide through targeting cyclin E1 in glioma cells

H Wang, S Ren, Y Xu, W Miao, X Huang, Z Qu… - Anti-cancer …, 2019 - journals.lww.com
Glioma is the most common malignant tumor of the central nervous system with poor
survival. Temozolomide (TMZ) is the first-line chemotherapy drug for initial and recurrent …