Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritis

Y Nam, SM Jung, YA Rim, H Jung, K Lee, N Park… - PLoS …, 2018 - journals.plos.org
It is unclear how systemic administration of mesenchymal stem cells (MSCs) controls local
inflammation. The aim of this study was to evaluate the therapeutic effects of human MSCs …

Immunosuppressive effects of mesenchymal stem cells in collagen-induced mouse arthritis

F Mao, WR Xu, H Qian, W Zhu, YM Yan, QX Shao… - Inflammation …, 2010 - Springer
Objective The objective of this study was to investigate the efficacy of mesenchymal stem
cell (MSC) in the treatment of arthritis. Methods Mesenchymal stem cells were injected …

Intra‐articular injection of human synovial membrane‐derived mesenchymal stem cells in murine collagen‐induced arthritis: assessment of immunomodulatory …

M Yan, X Liu, Q Dang, H Huang, F Yang… - Stem cells …, 2017 - Wiley Online Library
The aim of this study was to evaluate the efficacy of human synovial membrane‐derived
MSCs (SM‐MSCs) in murine collagen‐induced arthritis (CIA). Male mice (age 7–9 weeks) …

Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen‐induced arthritis

A Augello, R Tasso, SM Negrini… - Arthritis & …, 2007 - Wiley Online Library
Abstract Objective Mesenchymal stem cells (MSCs) are precursors of tissue of mesenchymal
origin, but they also have the capacity to regulate the immune response by suppressing T …

Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor α in collagen‐induced arthritis

F Djouad, V Fritz, F Apparailly… - Arthritis & …, 2005 - Wiley Online Library
Objective Adult mesenchymal stem cells (MSCs) represent promising tools for therapeutic
applications such as tissue engineering and cellular therapy. Recent data suggest that, due …

Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis

O Kehoe, A Cartwright, A Askari, AJ El Haj… - Journal of translational …, 2014 - Springer
Background Rheumatoid arthritis (RA) is a debilitating and painful disease leading to
increased morbidity and mortality and novel therapeutic approaches are needed. The …

Mesenchymal stem cells are conditionally therapeutic in preclinical models of rheumatoid arthritis

A Papadopoulou, M Yiangou, E Athanasiou… - Annals of the …, 2012 - ard.bmj.com
Objective The role of mesenchymal stem cells (MSC) in experimental arthritis is undoubtedly
conflicting. This study explored the effect of bone marrow-derived MSC in previously …

Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist

K Lee, N Park, H Jung, YA Rim, Y Nam, J Lee, SH Park… - PloS one, 2018 - journals.plos.org
Human bone marrow-derived mesenchymal stem cells (MSCs) have been observed to
inhibit arthritis in experimental animal models such as collagen-induced arthritis. However …

[HTML][HTML] Mesenchymal stem cells markedly suppress inflammatory bone destruction in rats with adjuvant-induced arthritis

T Takano, YJ Li, A Kukita, T Yamaza, Y Ayukawa… - Laboratory …, 2014 - Elsevier
Mesenchymal stem cells (MSCs) have potential to differentiate into multiple cell lineages.
Recently, it was shown that MSCs also have anti-inflammatory and immunomodulatory …

Treatment of collagen-induced arthritis using immune modulatory properties of human mesenchymal stem cells

KH Park, CH Mun, MI Kang, SW Lee… - Cell …, 2016 - journals.sagepub.com
Mesenchymal stem cells (MSCs) have immune modulatory properties. We investigated the
potential therapeutic effects of human bone marrow (BM)-, adipose tissue (AD)-, and cord …