Critique of current views on receptors, and a new general theory of receptor location and action in vivo

H Hillman - Medical Hypotheses, 1988 - Elsevier
Abstract The Davson-Danielli model of the cell membrane accounted for nearly all the space
within it by suggesting that it was composed of structural proteins and lipids; this would leave …

Recent advances in receptor research.

M Schachter - Postgraduate Medical Journal, 1989 - ncbi.nlm.nih.gov
Pharmacology is the science of receptors. This has been appreciated ever since
pharmacology began to emerge as a separate discipline. Langley'and Ehrlich2 proposed …

[引用][C] Theoretical pharmacology: the quantitative identification of receptors

RJ Tallarida - Trends in Pharmacological Sciences, 1981 - Elsevier
EJ Ari~ ns, for the rc,~ eptor etmccpt, once: only a theoretical construct, is now very much
one of the trends in pharmacologk tl thinking. Besides providing a theoretical framework for …

Specificity criteria for receptor sites in binding studies

PM Laduron - Investigation of Membrane-Located Receptors, 1984 - Springer
A 'binding site'is not synonymous with 'receptor site': biochemical criteria [saturable,
displaceable, high affinity, stereospecific,……) remain insufficient. There is no receptor …

Receptor mechanisms

RF Furchgott - Annual review of pharmacology, 1964 - annualreviews.org
It is common practice to interpret the effect of a given drug on a given effector system in
terms of an interaction between the drug and a specific receptive substance or receptor of …

A critical survey of receptor theories of drug action

D Mackay - Kinetics of drug action, 1977 - Springer
A drug may be defined as a chemical compound which modifies the properties of living cells.
The result of the action of a drug may be observed on single cells, isolated tissues, or whole …

The development of receptor theory

J Parascandola - Standardizing Pharmacology: Assays and …, 2023 - books.google.com
1.1 Background The fact that drugs may exert a selective action on specific organs has long
been recognized empirically and expressed vaguely in the traditional designation of certain …

Pharmacological receptors: The membrane receptors for neurotransmitters and drugs

J Vetulani - Acta Physiologica Polonica, 1988 - agro.icm.edu.pl
PHARMACOLOGICAL RECEPToRs. Page 1 ACTA PHYSIOL, POL., 1988, 39, 2 JERZY
VETULANI PHARMACOLOGICAL RECEPToRs. THE MEMBRANE RECEPTORS FOR …

[引用][C] On sensitiveness to drugs in animals and men

WS van Leeuwen - Journal Pharmacology and Experimental Therapeutics, 1924

[引用][C] Some introductory remarks on the conception of receptors

DK De Jongh - Molecular Pharmacology, 1964 - Elsevier