A modification of receptor theory. 1956.
RP Stephenson - British journal of pharmacology, 1997 - europepmc.org
It is usually supposed that a drug combines with some part of a tissue as a necessary step in
producing its action on that tissue. This view was expressed by Langley in 1878 while …
producing its action on that tissue. This view was expressed by Langley in 1878 while …
[引用][C] Relationship between drug distribution and therapeutic effects in man
ES Vesell - Annual Review of Pharmacology, 1974 - annualreviews.org
The intensity and duration of therapeutic effects derived from drugs other than those exerting
an immediate, irreversible action depend theoretically on maintaining ade quate …
an immediate, irreversible action depend theoretically on maintaining ade quate …
Methods in pharmacology
A Schwartz - 1971 - Springer
The death of Sir Henry Hallett Dale two years ago brought to a close an era which was
characterized by tremendous pharmacologic advancements. During this period, the …
characterized by tremendous pharmacologic advancements. During this period, the …
[引用][C] Membrane structure and drug actions
T Peters - Naunyn-Schmiedeberg's Archives of Pharmacology, 1977 - Springer
The pioneering work of GORTER and GRENDEL (1925) and of FRICKE (t925) producing
early evidence for the presence of a continuous lipid layer of blmolecular thickness …
early evidence for the presence of a continuous lipid layer of blmolecular thickness …
Receptors as defined by their pharmacological properties
WDM Paton - Molecular properties of drug receptors, 1970 - books.google.com
THE pharmacological knowledge which has led to, and to some extent defined, the idea of
the drug receptor can be arranged in three parts, concerned with (a) structure-action …
the drug receptor can be arranged in three parts, concerned with (a) structure-action …
[引用][C] Some features of modern pharmacology
VV Zakusov - Pharmacological Research Communications, 1980 - Elsevier
Pharlhdcological R~.search Communications, VoL 12, IVo. 3, 1980 Page 1 Pharlhdcological
R~.search Communications, VoL 12, IVo. 3, 1980 233 SOME FEATURES OF MODERN …
R~.search Communications, VoL 12, IVo. 3, 1980 233 SOME FEATURES OF MODERN …
[图书][B] Receptors in the Nervous System: Volume 6
A Lajtha - 2013 - books.google.com
A major advance in the biological sciences in the past decade has been the biochemical
identification of cell membrane receptors. The existence of re ceptor substances on the …
identification of cell membrane receptors. The existence of re ceptor substances on the …
Use of the biological stimulus in determining parameters of drug action, and its relationship to the drug effect A contribution to the theory of drug action
A Gero, RJ Tallarida - Journal of Theoretical Biology, 1977 - Elsevier
Drug action is considered a function of the biological stimulus, which in turn is proportional
to the receptor occupancy; but the nature of the functional relationship is unknown, as is also …
to the receptor occupancy; but the nature of the functional relationship is unknown, as is also …