[HTML][HTML] TERT Promoter Mutations in Thyroid Cancer
Two mutations (C228T and C250T) in the promoter region of the telomerase reverse
transcriptase (TERT) have recently been described in different types of cancer including …
transcriptase (TERT) have recently been described in different types of cancer including …
[HTML][HTML] TERT promoter mutations in thyroid cancer: a report from a Middle Eastern population
E Qasem, AK Murugan, H Al-Hindi… - Endocrine-related …, 2015 - erc.bioscientifica.com
Telomerase reverse transcriptase (TERT) promoter mutations C228T and C250T have
recently been described in follicular cell-derived thyroid cancer (TC) in patients from North …
recently been described in follicular cell-derived thyroid cancer (TC) in patients from North …
Telomerase in differentiated thyroid cancer: promoter mutations, expression and localization
M Muzza, C Colombo, S Rossi, D Tosi, V Cirello… - Molecular and cellular …, 2015 - Elsevier
Abstract Telomerase-reverse-transcriptase (TERT) promoter mutations have been recently
described in tumors. In the present large series, TERT mutations were found in 12% of …
described in tumors. In the present large series, TERT mutations were found in 12% of …
[HTML][HTML] TERT promoter mutations in thyroid cancer
R Liu, M Xing - Endocrine-related cancer, 2016 - erc.bioscientifica.com
The 2013 discovery of Telomerase reverse transcriptase (TERT) promoter mutations chr5,
1,295,228 C> T (C228T) and 1,295,250 C> T (C250T) in thyroid cancer represents an …
1,295,228 C> T (C228T) and 1,295,250 C> T (C250T) in thyroid cancer represents an …
Frequent Somatic TERT Promoter Mutations in Thyroid Cancer: Higher Prevalence in Advanced Forms of the Disease
Background: TERT encodes the reverse transcriptase component of telomerase, which adds
telomere repeats to chromosome ends, thus enabling cell replication. Telomerase activity is …
telomere repeats to chromosome ends, thus enabling cell replication. Telomerase activity is …
TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas
M Melo, AG da Rocha, J Vinagre… - The Journal of …, 2014 - academic.oup.com
Context: Telomerase promoter mutations (TERT) were recently described in follicular cell-
derived thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers …
derived thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers …
[PDF][PDF] TERT promoter mutations and long-term survival in patients with thyroid cancer
TH Kim, YE Kim, S Ahn, JY Kim, CS Ki… - Endocr Relat …, 2016 - scholar.archive.org
TERT promoter mutations are emerging prognostic biomarkers in multiple cancers and are
found in highly aggressive thyroid cancer. Our aim is to investigate the prognostic value of …
found in highly aggressive thyroid cancer. Our aim is to investigate the prognostic value of …
[HTML][HTML] TERT promoter mutations identify a high-risk group in metastasis-free advanced thyroid carcinoma
C Bournaud, F Descotes, M Decaussin-Petrucci… - European Journal of …, 2019 - Elsevier
Background TERT promoter mutations are associated with adverse clinicopathological
characteristics in thyroid carcinomas and considered as a major indicator of poor outcomes …
characteristics in thyroid carcinomas and considered as a major indicator of poor outcomes …
[HTML][HTML] Highly prevalent TERT promoter mutations in aggressive thyroid cancers
Abstract Mutations 1 295 228 C> T and 1 295 250 C> T (termed C228T and C250T
respectively), corresponding to− 124 C> T and− 146 C> T from the translation start site in the …
respectively), corresponding to− 124 C> T and− 146 C> T from the translation start site in the …
Clinicopathological indicators for TERT promoter mutation in papillary thyroid carcinoma
Objective Mutations in the telomerase reverse transcriptase (TERT) promoter have been
reported as a convincing prognostic factor in papillary thyroid carcinomas (PTCs). We aimed …
reported as a convincing prognostic factor in papillary thyroid carcinomas (PTCs). We aimed …