Roles of VEGF-A signalling in development, regeneration, and tumours

K Matsumoto, M Ema - The journal of biochemistry, 2014 - academic.oup.com
Angiogenesis, the formation of new networks of blood vessels, has essential roles in
embryonic development, organ homeostasis and disease progression. Several signalling …

VEGF receptor signaling and endothelial function

S Kliche, J Waltenberger - IUBMB life, 2001 - Wiley Online Library
Angiogenesis, the formation of new blood vessels from preexisting ones, is a central process
during normal development and during pathological repair. Vascular endothelial growth …

VEGF signaling: Role in angiogenesis and beyond

P Shaw, SKD Dwivedi, R Bhattacharya… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Angiogenesis is a crucial process for tissue development, repair, and tumor survival.
Vascular endothelial growth factor (VEGF) is a key driver secreted by cancer cells …

Exploring the intracrine functions of VEGF-A

S Wiszniak, Q Schwarz - Biomolecules, 2021 - mdpi.com
Vascular endothelial growth factor A (VEGF-A or VEGF) is a highly conserved secreted
signalling protein best known for its roles in vascular development and angiogenesis. Many …

Signaling pathways induced by vascular endothelial growth factor

B Larrivee, A Karsan - International journal of …, 2000 - spandidos-publications.com
Vasculogenesis and angiogenesis are the mechanisms responsible for the development of
the blood vessels. Angiogenesis refers to the formation of capillaries from pre-existing …

VEGFs, receptors and angiogenesis

T Veikkola, K Alitalo - Seminars in cancer biology, 1999 - Elsevier
Angiogenesis, the formation of new blood vessels from pre–-existing ones, is central for both
normal development and homeostasis as well as in certain pathological conditions. The …

Vascular endothelial growth factor signaling pathways: therapeutic perspective

M Kowanetz, N Ferrara - Clinical Cancer Research, 2006 - AACR
The establishment of a vascular supply is one of the earliest and most important events
occurring during embryonic development. Growth and maturation of a functional vascular …

Functions of the VEGF/VEGF receptor system in the vascular system

G Breier - Seminars in thrombosis and hemostasis, 2000 - thieme-connect.com
The vascular endothelial growth factor (VEGF)/VEGF receptor system plays a central
regulatory role in physiological and pathological angiogenesis. During embryogenesis, the …

[HTML][HTML] The role of VEGF in cancer-induced angiogenesis and research progress of drugs targeting VEGF

S Ghalehbandi, J Yuzugulen, MZI Pranjol… - European Journal of …, 2023 - Elsevier
Angiogenesis is a double-edged sword; it is a mechanism that defines the boundary
between health and disease. In spite of its central role in physiological homeostasis, it …

Biology and therapeutic targeting of vascular endothelial growth factor A

L Pérez-Gutiérrez, N Ferrara - Nature Reviews Molecular Cell Biology, 2023 - nature.com
The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …