Pathophysiology of paroxysmal and persistent atrial fibrillation: rotors, foci and fibrosis
Recent advances in our understanding of the mechanisms underlying atrial fibrillation (AF)
have further underscored the complex pathophysiological basis of the arrhythmia. It has …
have further underscored the complex pathophysiological basis of the arrhythmia. It has …
Atrial fibrillation from the pathologist's perspective
D Corradi - Cardiovascular pathology, 2014 - Elsevier
Atrial fibrillation (AF), the most common sustained cardiac arrhythmia encountered in clinical
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …
Atrial fibrosis and substrate based characterization in atrial fibrillation: time to move forwards
JX Quah, D Dharmaprani, K Tiver… - Journal of …, 2021 - Wiley Online Library
Atrial fibrillation (AF) is the most commonly encountered cardiac arrhythmia in clinical
practice. However, current therapeutic interventions for atrial fibrillation have limited clinical …
practice. However, current therapeutic interventions for atrial fibrillation have limited clinical …
[HTML][HTML] The atrium in atrial fibrillation–a clinical review on how to manage atrial fibrotic substrates
Atrial fibrillation (AF) is the most common sustained arrhythmia in the population and is
associated with a significant clinical and economic burden. Rigorous assessment of the …
associated with a significant clinical and economic burden. Rigorous assessment of the …
The value of basic research insights into atrial fibrillation mechanisms as a guide to therapeutic innovation: a critical analysis
Atrial fibrillation (AF) is an extremely common clinical problem associated with increased
morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation …
morbidity and mortality. Current antiarrhythmic options include pharmacological, ablation …
Fibrosis and atrial fibrillation: computerized and optical mapping: a view into the human atria at submillimeter resolution
Recent studies strongly suggest that the majority of atrial fibrillation (AF) patients with
diagnosed or subclinical cardiac diseases have established or even pre-existing fibrotic …
diagnosed or subclinical cardiac diseases have established or even pre-existing fibrotic …
[HTML][HTML] Atrial fibrillation: mechanisms, therapeutics, and future directions
J Pellman, F Sheikh - Comprehensive Physiology, 2015 - ncbi.nlm.nih.gov
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, affecting 1% to 2% of the
general population. It is characterized by rapid and disorganized atrial activation leading to …
general population. It is characterized by rapid and disorganized atrial activation leading to …
Human atrial fibrillation substrate: towards a specific fibrotic atrial cardiomyopathy
H Kottkamp - European heart journal, 2013 - academic.oup.com
The atrial structure/substrate of patients with atrial fibrillation (AF) and clinically similar
characteristics can present very differently, and also the 'phenotype'(ie paroxysmal …
characteristics can present very differently, and also the 'phenotype'(ie paroxysmal …
Intermittent drivers anchoring to structural heterogeneities as a major pathophysiological mechanism of human persistent atrial fibrillation
M Haissaguerre, AJ Shah, H Cochet… - The Journal of …, 2016 - Wiley Online Library
The mechanisms responsible for perpetuation of human persistent atrial fibrillation (AF) are
controversial and probably vary between individuals. A wide spectrum of mechanisms have …
controversial and probably vary between individuals. A wide spectrum of mechanisms have …
Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation
Atrial fibrillation (AF) is an extremely prevalent arrhythmia that presents a wide range of
therapeutic challenges. AF usually begins in a self-terminating paroxysmal form (pAF). With …
therapeutic challenges. AF usually begins in a self-terminating paroxysmal form (pAF). With …