Effects of isoflurane concentration on the activity of pontomedullary raphe and medial reticular neurons in the rat

CG Leung, P Mason - Brain research, 1995 - Elsevier
Neurons in the pontomedullary raphe magnus (RM) and adjacent nucleus reticularis
paragigantocellularis pars α (NRPGα) are thought to participate in the modulation of spinal …

The effect of alpha2-adrenergic drugs on the activity of neurons in the rat nucleus raphe magnus in vitro

T Kanda, Y Ohta, A Kida, O Kemmotsu - Anesthesia & Analgesia, 1999 - journals.lww.com
The nucleus raphe magnus (NRM) is an important descending inhibitory system for pain
transmission. We tested whether clonidine, an alpha 2-adrenergic agonist, and yohimbine …

Physiological functions of pontomedullary raphe and medial reticular neurons

P Mason, CG Leung - Progress in Brain Research, 1996 - Elsevier
Publisher Summary This chapter focuses on the nociceptive modulatory role of neurons in
the pontomedullary raphe magnus (RM) and the adjacent nucleus reticularis …

Activity changes in rat raphe magnus neurons at different concentrations of fentanyl in vitro

Y Ohta, MES Alojado, O Kemmotsu - Anesthesia & Analgesia, 1995 - journals.lww.com
The nucleus raphe magnus (NRM) is an important descending pain inhibitory system. We
postulated that the analgesic action of supraspinally administered opiates results from …

Anesthetics block excitation with various effects on inhibition in MRF neurons

K Shimoji, H Fujioka, T Ebata - Brain research, 1984 - Elsevier
The effects of isoflurane and halothane on the behavior of mesencephalic reticular neurons
in the rat were studied by long-term extracellular microelectrode recording. Both anesthetics …

The effects of periaqueductal gray and nucleus raphe magnus stimulation on the spontaneous and noxious-evoked activity of lateral reticular nucleus neurons in …

ML Sotgiu - Brain research, 1987 - Elsevier
In urethane-anesthetized rabbits the effects of periaqueductal gray (PAG) and nucleus raphe
magnus (NRM) stimulation on the spontaneous and the noxious-evoked activity of the lateral …

The effect of clonidine on the activity of neurons in the rat dorsal raphe nucleus in vitro

MES Alojado, Y Ohta, O Kemmotsu - Anesthesia & Analgesia, 1994 - journals.lww.com
The dorsal raphe (DR) nucleus is a system of nuclei in the midline of the lower brainstem,
which is considered one of the most important nuclei in the modulation of pain in the central …

Inhibition of spinal nociceptive information by stimulation in midbrain of the cat is blocked by lidocaine microinjected in nucleus raphe magnus and medullary reticular …

GF Gebhart, J Sandkuhler… - Journal of …, 1983 - journals.physiology.org
The organization in the brain stem of descending inhibitory control of spinal nociceptive
information was studied in anesthetized, paralyzed cats by quantitatively evaluating the …

Stimulation-produced descending inhibition from the periaqueductal gray and nucleus raphe magnus in the rat: mediation by spinal monoamines but not opioids

LD Aimone, SL Jones, GF Gebhart - Pain, 1987 - journals.lww.com
Focal electrical stimulation in the midbrain periaqueductal gray (PAG) or medullary nucleus
raphe magnus (NRM) inhibits spinal nociceptive transmission and nociceptive reflexes. The …

Relative contributions of the nucleus raphe magnus and adjacent medullary reticular formation to the inhibition by stimulation in the periaqueductal gray of a spinal …

J Sandkühler, GF Gebhart - Brain research, 1984 - Elsevier
The organization in the brainstem of descending pathways of spinal inhibition was
examined in the lightly pentobarbital-anesthetized rat. Thresholds for focal electrical …