Effects of second and third generation oral contraceptives and their respective progestagens on the coagulation system in the absence or presence of the factor V …

JM Kemmeren, A Algra, JCM Meijers… - Thrombosis and …, 2002 - thieme-connect.com
Compared to second generation, the use of third generation oral contraceptives has been
associated with an increased risk of venous thrombosis especially in women with the factor …

Effect of second-and third-generation oral contraceptives on fibrinolysis in the absence or presence of the factor V Leiden mutation

JM Kemmeren, A Algra, JCM Meijers… - Blood coagulation & …, 2002 - journals.lww.com
Third-generation oral contraceptives (OC) have been associated with an increased risk of
venous thrombosis compared with second-generation OC. To find an explanation for this …

Enhancement by factor V Leiden mutation of risk of deep-vein thrombosis associated with oral contraceptives containing a third-generation progestagen

KWM Bloemenkamp, FM Helmerhorst, FR Rosendaal… - The Lancet, 1995 - thelancet.com
Recent concern about the safety of combined oral contraceptives (OCs) with third-
generation progestagens prompted an examination of data from a population-based case …

Are factor V Leiden carriers who use oral contraceptives at extreme risk for venous thromboembolism?

M Spannagl, LAJ Heinemann… - The European Journal of …, 2000 - Taylor & Francis
Background Major concern was raised by an earlier study regarding oral contraceptive use
in women with the factor V Leiden mutation. A more than 30-fold increase in relative risk for …

Association of venous thromboembolism with hormonal contraception and thrombophilic genotypes

A Bergendal, I Persson, J Odeberg… - Obstetrics & …, 2014 - journals.lww.com
OBJECTIVE: To investigate associations between combined hormonal contraception and
progestogen-only contraception and risks of venous thromboembolism by progestogen and …

Factor V Leiden: should all women be screened prior to commencing the contraceptive pill?

ID Walker - Blood reviews, 1999 - Elsevier
It has been evident for over 30 years that combined oral contraceptive pills (OCP) increase
the risk of venous thromboembolism. Recently, it has been suggested that there is an …

Effect of second- and third-generation oral contraceptives on the protein C system in the absence or presence of the factor VLeiden mutation: a randomized trial

JM Kemmeren, A Algra, JCM Meijers, G Tans… - Blood, 2004 - ashpublications.org
A plausible mechanism to explain thrombotic risk differences associated with the use of
second-and third-generation oral contraceptives (OCs), particularly in carriers of factor …

Type of combined contraceptives, factor V Leiden mutation and risk of venous thromboembolism

J Hugon-Rodin, MH Horellou, J Conard… - Thrombosis and …, 2018 - thieme-connect.com
Objective This article estimates the interaction between types of combined hormonal
contraception (CHC) and factor V Leiden (FVL) mutation on the risk of venous thrombosis …

Thrombotic risk during oral contraceptive use and pregnancy in women with factor V Leiden or prothrombin mutation: a rational approach to contraception

EFW van Vlijmen, NJGM Veeger… - Blood, The Journal …, 2011 - ashpublications.org
Current guidelines discourage combined oral contraceptive (COC) use in women with
hereditary thrombophilic defects. However, qualifying all hereditary thrombophilic defects as …

Third-generation oral contraceptive and deep venous thrombosis: from epidemiologic controversy to new insight in coagulation

JP Vandenbroucke, FM Helmerhorst… - American journal of …, 1997 - Elsevier
Four epidemiologic studies showed a twofold increase in risk of deep venous thrombosis
with the use of oral contraceptives containing third-generation progestins, relative to second …