With ever-increasing elder populations, age-related cognitive decline, which is
characterized as a gradual decline in cognitive capacity in the aging process, has turned out …

Age-associated cognitive decline is an inevitable phenomenon that predisposes individuals
for neurological and psychiatric disorders eventually affecting the quality of life. Scientists …

Aging is associated with gradual deterioration of physiological and biochemical functions,
including cognitive decline. Transcriptome profiling of brain samples from individuals of …

Determining the genetic influences on cognitive ability in old age and in cognitive ageing
are important areas of research in an increasingly ageing society. Heritability studies …

Aging is associated with cognitive decline and increased vulnerability to neurodegenerative
diseases. The progressive extension of the average human lifespan is bound to lead to a …

Age-related cognitive decline is likely promoted by accumulated brain injury due to chronic
conditions of aging, including neurodegenerative and vascular disease. Because common …

Knowledge of genetic influences on cognitive aging can constrain and guide interventions
aimed at limiting age-related cognitive decline in older adults. Progress in understanding the …

Human longevity and healthy aging show moderate heritability (20%–50%). We conducted
a meta-analysis of genome-wide association studies from 9 studies from the Cohorts for …

As the world's population ages, the age-related cognitive decline presents a great challenge
to world's healthcare systems. One of the molecular mechanisms implicated in cognitive …

The genetic protective factors for cognitive decline in aging remain unknown. Predicting an
individual's rate of cognitive decline—or with better cognitive resilience—using genetics will …