Effects of oral valganciclovir prophylaxis for cytomegalovirus infection in heart transplant patients

AO Doesch, J Repp, N Hofmann, C Erbel… - Drug Design …, 2012 - Taylor & Francis
Background Cytomegalovirus (CMV) infection is a serious complication following heart
transplantation. This study (June 2003–January 2010) retrospectively assessed the effects …

Experience with low-dose valganciclovir prophylaxis in adult liver transplant recipients

R Dupuis, M Harris, K Gillis, D Gerber, J Fair… - Transplantation …, 2007 - Elsevier
Valganciclovir (VGCV) is considered the agent of choice after organ transplant for
cytomegalovirus (CMV) prophylaxis. The purpose of this retrospective study was to …

Randomised comparison of ganciclovir and high-dose acyclovir for long-term cytomegalovirus prophylaxis in liver-transplant recipients

DJ Winston, D Wirin, A Shaked, RW Busuttil - The Lancet, 1995 - thelancet.com
Despite current approaches to prophylaxis, cytomegalovirus (CMV) continues to be a
common cause of infection and disease in solid-organ-transplant patients. Thus, we …

Changing impact of cytomegalovirus in liver transplantation–a single centre experience of more than 1000 transplantations without ganciclovir prophylaxis

D Seehofer, N Rayes, UP Neumann… - Transplant …, 2005 - Wiley Online Library
As cytomegalovirus (CMV) disease was a leading cause of death following liver
transplantation in earlier reports, general CMV prophylaxis is widely used. We re‐evaluated …

[HTML][HTML] Anti-cytomegalovirus prophylaxis in solid-organ transplant recipients

ME Falagas, KZ Vardakas - Clinical microbiology and infection, 2006 - Elsevier
Ganciclovir and its prodrug, valganciclovir, are more effective than acyclovir in preventing
cytomegalovirus (CMV) infection and disease in solid-organ transplant recipients. However …

Oral ganciclovir versus valganciclovir for cytomegalovirus prophylaxis in high‐risk liver transplant recipients

RL Brady, K Green, C Frei… - Transplant Infectious …, 2009 - Wiley Online Library
This retrospective review compared oral valganciclovir (VGCV) 450 mg daily for 6 months
versus oral ganciclovir (GCV) 1000 mg 3 times daily for 3 months in preventing …

[HTML][HTML] Primary CMV infections are common in kidney transplant recipients after 6 months valganciclovir prophylaxis

I Helanterä, L Kyllönen, I Lautenschlager… - American Journal of …, 2010 - Elsevier
Prolonging cytomegalovirus (CMV) prophylaxis in CMV seronegative recipients of a kidney
from CMV seropositive donor (D+/R–) may reduce the incidence of late infections. We …

Prevention of cytomegalovirus disease in solid organ transplant patients: Prophylactic versus preemptive therapy

GM Baillie - American journal of health-system pharmacy, 2006 - academic.oup.com
Purpose. The advantages and disadvantages of universal prophylaxis and preemptive
therapy and current evidence-based recommendations for preventing cytomegalovirus …

Incidence and severity of cytomegalovirus infection in seropositive heart transplant recipients

BJ Gardiner, JP Bailey, MA Percival… - Clinical …, 2023 - Wiley Online Library
Background The frequency and significance of cytomegalovirus (CMV) infection in
seropositive (R+) heart transplant recipients (HTR) is unclear, with preventative …

Prophylactic CMV therapy does not improve three‐yr patient and graft survival compared to preemptive therapy

J Werzowa, B Schwaiger, M Hecking… - Clinical …, 2015 - Wiley Online Library
Despite increasing evidence in favor of prophylactic valganciclovir treatment in kidney
transplant recipients for the prevention of cytomegalovirus (CMV) infection, the impact of …