Immune monitoring-guided versus fixed duration of antiviral prophylaxis against cytomegalovirus in solid-organ transplant recipients: a multicenter, randomized …

O Manuel, M Laager, C Hirzel… - Clinical infectious …, 2024 - academic.oup.com
Background The use of assays detecting cytomegalovirus (CMV)–specific T cell–mediated
immunity may individualize the duration of antiviral prophylaxis after transplantation …

Prophylaxis for CMV should now replace pre‐emptive therapy in solid organ transplantation

GD Hart, CV Paya - Reviews in medical virology, 2001 - Wiley Online Library
Cytomegalovirus is a significant cause of morbidity and mortality in transplantation.
Controversy exists concerning whether prophylactic or pre‐emptive therapy is the optimal …

Valganciclovir preemptive therapy for the prevention of cytomegalovirus disease in high-risk seropositive solid-organ transplant recipients

C Díaz-Pedroche, C Lumbreras, R San Juan… - …, 2006 - journals.lww.com
Background. The role of valganciclovir in the prevention of cytomegalovirus (CMV) disease
in high-risk seropositive transplant patients is not known. Methods. We prospectively …

Allograft rejection predicts the occurrence of late-onset cytomegalovirus (CMV) disease among CMV-mismatched solid organ transplant patients receiving prophylaxis …

RR Razonable, A Rivero, A Rodriguez… - The Journal of …, 2001 - academic.oup.com
The natural history of cytomegalovirus (CMV) disease associated with solid organ
transplantation has been modified as a result of the widespread use of antiviral prophylaxis …

Valganciclovir prophylaxis versus preemptive therapy in cytomegalovirus-positive renal allograft recipients: 1-year results of a randomized clinical trial

O Witzke, IA Hauser, M Bartels, G Wolf, H Wolters… - …, 2012 - journals.lww.com
Background. Cytomegalovirus (CMV) prevention can be achieved by prophylaxis or
preemptive therapy. We performed a prospective randomized trial to determine whether …

The value of pre-emptive therapy for cytomegalovirus after liver transplantation

V Müller, A Perrakis, J Meyer, T Förtsch, K Korn… - Transplantation …, 2012 - Elsevier
BACKGROUND: Cytomegalovirus (CMV) infections are among the most common infections
following liver transplantation. The main preventive methods for CMV infections are …

[HTML][HTML] Cytomegalovirus disease in high-risk transplant recipients despite ganciclovir or valganciclovir prophylaxis

E Akalin, V Sehgal, S Ames, S Hossaic, L Daly… - American Journal of …, 2003 - Elsevier
The clinical patterns and predictors of cytomegalovirus (CMV) disease in kidney and/or
pancreas transplant patients on ganciclovir (1.0 g po tid) or valganciclovir (450 mg po qd) …

Comparison of preemptive therapy and antiviral prophylaxis for prevention of cytomegalovirus in seropositive liver transplant recipients

AW Liu, K Jutivorakool, CE Fisher, RM Rakita… - …, 2018 - journals.lww.com
Background Few studies have directly compared preemptive therapy (PET) and antiviral
prophylaxis (AP) for prevention of cytomegalovirus (CMV) disease in CMV seropositive (R+) …

[HTML][HTML] New developments in the management of cytomegalovirus infection after solid organ transplantation

AJ Eid, RR Razonable - Drugs, 2010 - Springer
Despite remarkable advances in the diagnostic and therapeutic modalities for its
management, cytomegalovirus (CMV) remains one of the most important pathogens …

[HTML][HTML] Cytomegalovirus infection after liver transplantation: current concepts and challenges

RR Razonable - World journal of gastroenterology: WJG, 2008 - ncbi.nlm.nih.gov
Cytomegalovirus (CMV) is a common viral pathogen that influences the outcome of liver
transplantation. In addition to the direct effects of CMV syndrome and tissue-invasive …