Prospective randomized trial to assess the value of preemptive oral therapy for CMV infection following liver transplantation

N Rayes, D Seehofer, CA Schmidt, H Oettle… - …, 2001 - journals.lww.com
Background. With the development of sensitive tests to detect cytomegalovirus (CMV)
viremia, preemptive approaches become a reasonable alternative to general CMV …

[HTML][HTML] Valganciclovir for cytomegalovirus prevention in solid organ transplant patients: an evidence-based reassessment of safety and efficacy

AC Kalil, AG Freifeld, ER Lyden, JA Stoner - Plos one, 2009 - journals.plos.org
Background Several anti-viral drugs have demonstrated efficacy in preventing
Cytomegalovirus (CMV) infections in solid organ transplant (SOT) patients. The recently …

Delayed graft function and rejection are risk factors for cytomegalovirus breakthrough infection in kidney transplant recipients

W Kleinherenbrink, M Baas, G Nakhsbandi… - Pharmacological …, 2021 - Elsevier
Breakthrough cytomegalovirus (CMV) disease during valganciclovir prophylaxis is rare but
may cause significant morbidity and even mortality. In order to identify patients at increased …

[PDF][PDF] Efficacy and safety of low‐dose valganciclovir in the prevention of cytomegalovirus disease in adult liver transplant recipients

JM Park, KD Lake, JD Arenas… - Liver …, 2006 - Wiley Online Library
The efficacy and safety of valganciclovir (VGCV) for cytomegalovirus (CMV) prophylaxis in
liver transplant recipients has not been established. We retrospectively compared the …

[HTML][HTML] Impact of antiviral preventive strategies on the incidence and outcomes of cytomegalovirus disease in solid organ transplant recipients

O Manuel, G Kralidis, NJ Mueller, HH Hirsch… - American journal of …, 2013 - Elsevier
We assessed the impact of antiviral prophylaxis and preemptive therapy on the incidence
and outcomes of cytomegalovirus (CMV) disease in a nationwide prospective cohort of solid …

High‐dose acyclovir prophylaxis reduces cytomegalovirus disease in liver transplant patients

L Barkholt, I Lewensohn‐Fuchs… - Transplant infectious …, 1999 - Wiley Online Library
Cytomegalovirus (CMV) is still a major pathogen in liver transplantation (LTX). The clinical
efficacy of prophylactic high‐dose acyclovir therapy (800 mg qid) was assessed for the …

Unraveling the biologic basis of late-onset cytomegalovirus disease in high-risk organ transplant recipients

N Singh - Transplantation, 2011 - journals.lww.com
Late-onset cytomegalovirus (CMV) disease, defined as CMV disease occurring after 3
months posttransplant is a significant complication with the use of prophylaxis, particularly in …

Cost-effectiveness of different strategies of cytomegalovirus prophylaxis in orthotopic liver transplant recipients

A Das - Hepatology, 2000 - journals.lww.com
Cytomegalovirus (CMV) is an important cause of morbidity and mortality in liver transplant
recipients and several different strategies of CMV chemoprophylaxis are in practice. A cost …

Selective low-dose valganciclovir for prevention of cytomegalovirus disease following kidney transplantation

YP Avidan, M Paul, R Rahamimov, J Bishara, Z Samra… - Journal of Infection, 2008 - Elsevier
OBJECTIVES: To assess the safety of a cytomegalovirus prophylaxis regimen using
selective low-dose valganciclovir. METHODS: Retrospective before–after comparison …

Universal valganciclovir prophylaxis significantly reduces episodes of first-year cytomegalovirus disease and biopsy-proven acute rejection in kidney transplant …

PT Tu, KH Shu, CH Cheng, CH Chen, TM Yu… - Transplantation …, 2014 - Elsevier
Background Cytomegalovirus (CMV) remains the most critical viral pathogen after kidney
transplantation (KTx). The universal prophylaxis, but not pre-emptive therapy, could avoid …