A series of racemic 3-phenyl-5-methyl-2H, 5H-furan-2-ones related to a natural product,(−)
incrustoporine, was synthesized, and their antifungal activity evaluated. The key structural …

3-(Substituted phenyl)-5-acyloxymethyl-2 H, 5 H-furan-2-ones related to the natural product
(−) incrustoporine were synthesized and their in vitro antifungal activity evaluated. The …

Two series of 3-(substituted phenyl)-5-alkyl-2, 5-dihydrofuran-2-ones related to a natural
product,(−) incrustoporine, were synthesized and their in vitro antifungal activity evaluated …

In continuing the studies on the synthesis and evaluation of antifungal activity of the
analogues of (-) incrustoporine, the replacement of the phenyl moiety at C3 of the furanone …

A series of 3-aryl-5-acyloxymethyl-5, 6-dihydro-2H-pyran-2-ones, related to highly
antifungally active butenolides, was synthesized via cyclization of substituted δ-hydroxy …

In order to find new potential pesticide molecules with antifungal activities, we have
designed and synthesized a series of amino acid-oriented poly-substituted tetramic acid …

Azole antifungals, including fluconazole, have long been the first-line antifungal agents in
the fight against fungal infections. The emergence of drug-resistant strains and the …

Three new γ-hydroxyl butenolides (1–3), a pair of new enantiomeric spiro-butenolides (4a
and 4b), a pair of enantiomeric cyclopentenones (5a new and 5b new natural), and six …

Guiding by an antifungal screening, seven mono-/bis-alkenoic acid derivatives (1‒7) were
isolated from an endophytic fungi Scopulariopsis candelabrum. Their chemical structures …

Triazoles have demonstrated significant efficacy in the treatment of fungal infections.
However, increasing drug resistance is a growing concern that negatively impacts their …