Molecular characterization of tumors has shifted cancer treatment strategies away from
nonspecific cytotoxic treatment of histology-specific tumors toward targeting of actionable …

Precision medicine has emerged as a tool to match patients with the appropriate treatment
based on the precise molecular features of an individual patient's tumor. Although examples …

Precision oncology is described as the matching of the most accurate and effective
treatments with the individual cancer patient. Identification of important gene mutations, such …

In this Special Series issue, Journal of Clinical Oncologypresents a systematic assessment
of cancer genomic information and its accelerating clinical impact. In the scientific literature …

Our understanding of the molecular mechanisms underlying cancer development and
evolution have evolved rapidly over recent years, and the variation from one patient to …

Based on early evidence of fossilized bone tumors that were found in ancient Egyptian
mummies, cancer is an ancient disease. 1 The term “carcinoma7 to refer to cancer was first …

You're living the good life—eating right, exercising, maintaining a healthy weight—doing all
the recommended things to maintain a healthy and productive lifestyle. Then, Bam! Your …

In recent years, biotechnological breakthroughs have led to identification of complex and
unique biologic features associated with carcinogenesis. Tumor and cell-free DNA profiling …

Precision oncology has evolved into focusing on matching the most accurate and effective
treatments based not only on the genetic profile of the patient and his/her cancer, but also on …

Precision oncology, defined as molecular profiling of tumors to identify targetable alterations,
is rapidly developing and has entered the mainstream of clinical practice. Genomic testing …