The thymidine analog 18F-3′-deoxy-3′-fluorothymidine (FLT) is being used clinically for
PET imaging of tumor proliferation. Appropriate use of this tracer requires validating the …

Several new tracers are being developed for use with PET to assess pathways that are
altered in cancers, including energy use, cellular signaling, transport, and proliferation …

Purpose The aim of this study was to investigate the role of thymidine kinase 1 (TK 1) protein
in 3′-deoxy-3′-[18 F] fluorothymidine ([18 F] FLT) positron emission tomography (PET) …

3′-Deoxy-3′-[F-18] fluorothymidine (FLT) is under clinical evaluation as a metabolic probe
for imaging cell proliferation in vivo using positron emission tomography (PET). As part of …

Positron emission tomography (PET) using F-18 fluoro-3′-deoxy-3-L-fluorothymidine (FLT)
offers noninvasive assessment of cell proliferation in vivo. The most important application …

The use of radiolabeled thymidine (TdR) and thymidine analogs as PET-based tracers of
tumor growth rate is based on the assumption that measurement of uptake of these …

Assessing cellular proliferation provides a direct method to measure the in vivo growth of
cancer. We evaluated the application of a model of 3′-deoxy-3′-18F-fluorothymidine (18F …

3′-Deoxy-3′-18F-fluorothymidine (18F-FLT) is a PET imaging agent that shows promise
for studying cellular proliferation in human cancers. FLT is a nucleoside analog that enters …

Here we describe the evaluation of 3′-[18F] fluoro-3′-deoxythymidine {[18F]-FLT} as a
tracer for positron emission tomography (PET) in a murine model of B-cell lymphoma and in …

Deoxy-3′-[18F] fluorothymidine ([18F] FLT) has been proposed as a new marker for
imaging tumor proliferation by positron emission tomography (PET). The uptake of [18F] FLT …