Thirty-two cases of hereditary medullary thyroid carcinoma (HMTC) and 95 sporadic HMTC
(SHMTC), 44 familial papillary TC (FPTC), and 172 sporadic cases were comparatively …

Medical Research Institute of Radiology, Russian Academy Forty-eight cases of familial
disease (24 families)(4.3%) were identified among 1,118 patients with well-differentiated …

Powiązanie w 1993 r. mutacji w obrębie protoonkogenu RET z występowaniem postaci
rodzinnych raka rdzeniastego tarczycy (RRT) umożliwiło wdrożenie szczegółowych badań …

Medullary thyroid cancer (MTC) is a fairly rare disease, accounting for 5-7% of all cases of
thyroid cancer. The sporadic form of thyroid cancer is observed in 70-80% of cases, family …

Thyroid carcinoma is the most common malignancy of the endocrine system and its
incidence is still growing. The majority of thyroid tumors occur in sporadic form, however …

Introduction: The assessment of frequency and type of mutation and differences in prognosis
between sporadic and hereditary type of medullary thyroid carcinoma (MTC), based on own …

In hereditary MTC recommended age surgery in carriers of the mutation depends on its
localization in the gene RET, which determines the probable age of tumor onset …

Introduction: The aim of this study was to analyse the distribution and frequency of mutations
and their correlations with clinical phenotypes of patients with MTC, to reveal the differences …

The paper is focused on guidelines of practice in inherited medullary thyroid cancer,
diagnosed on the basis of DNA analysis. Identification of RET mutation implies further steps …

Medullary thyroid cancer (MTC) represents 2-8% of thyroid malignancies. Predominantly
MTC have sporadic nature but 20-30% of cases are hereditary caused by germ line …