Molecular cloning studies have revealed the existence of a large family of voltage-gated K+
channel genes expressed in mammalian brain. This molecular diversity underlies the vast …

In the mammalian nervous system, K+ channels regulate diverse aspects of neuronal
function and are encoded by a large set of K+ channel genes. The roles of different K+ …

Voltage-gated K+ channels control excitability in neuronal and various other tissues. We
identified three unique α-subunits of voltage-gated K+-channels in the human genome …

In the nervous system, a wide diversity of K+ channels are formed by the oligomeric
assembly of subunits encoded by a large number of K+ channel genes. The physiological …

Excitability and discharge behavior of neurons depends on the highly variable expression
pattern of voltage-dependent potassium (Kv) channels throughout the nervous system. To …

Depolarization-activated, Ca2+-independent K+ currents can be largely divided into delayed
rectifiers and transient A-type currents. In mammals, each of these subtypes exhibits large …

We determined the expression of Kv2 channel subunits in rat somatosensory and motor
cortex and tested for the contributions of Kv2 subunits to slowly inactivating K+ currents in …

Serôdio, Paulo and Bernardo Rudy. Differential expression of Kv4 K+ channel subunits
mediating subthreshold transient K+ (A-type) currents in rat brain. J. Neurophysiol. 79: 1081 …

Recent cloning of K+ channel β subunits revealed that these cytoplasmic polypeptides can
dramatically alter the kinetics of current inactivation and promote efficient glycosylation and …

1. Proteins of the Kv4 or Shal-related subfamily are key components of transient K+
channels (A channels) operating at subthreshold values of the membrane potential. We …