[HTML][HTML] Dysregulated metabolic pathways in age-related macular degeneration
Age-related macular degeneration is a major cause of vision impairment in the Western
world among people of 55 years and older. Recently we have shown that autophagy is …
world among people of 55 years and older. Recently we have shown that autophagy is …
[HTML][HTML] Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration
N Golestaneh, Y Chu, YY Xiao, GL Stoleru… - Cell death & …, 2018 - nature.com
Age-related macular degeneration (AMD) is a devastating neurodegenerative disease and a
major cause of blindness in the developed world. Owing to its complexity and the lack of an …
major cause of blindness in the developed world. Owing to its complexity and the lack of an …
[HTML][HTML] Metabolomics in age-related macular degeneration: a systematic review
XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2020 - iovs.arvojournals.org
Purpose: Age-related macular degeneration (AMD) is one of the leading causes of
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …
blindness among the elderly, and the exact pathogenesis of the AMD remains unclear. The …
[HTML][HTML] Human plasma metabolomics in age-related macular degeneration: meta-analysis of two cohorts
The pathogenesis of age-related macular degeneration (AMD), a leading cause of blindness
worldwide, remains only partially understood. This has led to the current lack of accessible …
worldwide, remains only partially understood. This has led to the current lack of accessible …
Human plasma metabolomics study across all stages of age-related macular degeneration identifies potential lipid biomarkers
Purpose To characterize the plasma metabolomic profile of patients with age-related
macular degeneration (AMD) using mass spectrometry (MS). Design Cross-sectional …
macular degeneration (AMD) using mass spectrometry (MS). Design Cross-sectional …
[HTML][HTML] Retinal remodeling and metabolic alterations in human AMD
BW Jones, RL Pfeiffer, WD Ferrell, CB Watt… - Frontiers in cellular …, 2016 - frontiersin.org
Age-related macular degeneration (AMD) is a progressive retinal degeneration resulting in
central visual field loss, ultimately causing debilitating blindness. AMD affects 18% of …
central visual field loss, ultimately causing debilitating blindness. AMD affects 18% of …
Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration
K Kaarniranta, D Sinha, J Blasiak, A Kauppinen… - Autophagy, 2013 - Taylor & Francis
Age-related macular degeneration (AMD) is a complex, degenerative and progressive eye
disease that usually does not lead to complete blindness, but can result in severe loss of …
disease that usually does not lead to complete blindness, but can result in severe loss of …
Autophagy in age‐related macular degeneration: a regulatory mechanism of oxidative stress
ZY Zhang, XL Bao, YY Cong, B Fan… - Oxidative medicine and …, 2020 - Wiley Online Library
Age‐related macular degeneration (AMD) is a leading cause of severe visual loss and
irreversible blindness in the elderly population worldwide. Retinal pigment epithelial (RPE) …
irreversible blindness in the elderly population worldwide. Retinal pigment epithelial (RPE) …
Oxidative stress, hypoxia, and autophagy in the neovascular processes of age‐related macular degeneration
J Blasiak, G Petrovski, Z Veréb… - BioMed research …, 2014 - Wiley Online Library
Age‐related macular degeneration (AMD) is the leading cause of severe and irreversible
loss of vision in the elderly in developed countries. AMD is a complex chronic …
loss of vision in the elderly in developed countries. AMD is a complex chronic …
Autophagy dysfunction, cellular senescence, and abnormal immune‐inflammatory responses in AMD: From mechanisms to therapeutic potential
S Wang, X Wang, Y Cheng, W Ouyang… - Oxidative medicine …, 2019 - Wiley Online Library
Age‐related macular degeneration (AMD) is a blinding disease caused by multiple factors
and is the primary cause of vision loss in the elderly. The morbidity of AMD increases every …
and is the primary cause of vision loss in the elderly. The morbidity of AMD increases every …