Inhalation therapy in invasive and noninvasive mechanical ventilation

R Dhand - Current opinion in critical care, 2007 - journals.lww.com
Pressurized metered-dose inhalers of bronchodilator and corticosteroid aerosols are more
efficient and convenient to use than nebulizers for routine therapy in ventilated patients …

Aerosol delivery during mechanical ventilation: from basic techniques to new devices

R Dhand - Journal of aerosol medicine and pulmonary drug …, 2008 - liebertpub.com
Pressurized metered-dose inhalers (pMDIs) and nebulizers are routinely employed for
aerosol delivery in mechanically ventilated patients. A significant proportion of the aerosol …

Utilization of bronchodilators in ventilated patients without obstructive airways disease

LH Chang, S Honiden, JA Haithcock, AM Das… - Respiratory …, 2007 - rc.rcjournal.com
OBJECTIVE: To examine physician practice in, and the costs of, prescribing inhaled
bronchodilators to mechanically ventilated patients who do not have obstructive lung …

Aerosol therapy during mechanical ventilation: getting ready for prime time

R Dhand - American journal of respiratory and critical care …, 2003 - atsjournals.org
Inhaled therapy has been routinely employed for over half a century in ambulatory patients
with respiratory disorders. In contrast, many barriers were previously thought to preclude …

Aerosol deposition in mechanically ventilated patients. Optimizing nebulizer delivery.

TG O'Riordan, LB Palmer… - American Journal of …, 1994 - atsjournals.org
Previous studies have suggested that nebulizers are inefficient in delivering aerosolized
medication to the lung in patients supported by mechanical ventilation. In a recent bench …

Bronchodilator delivery with metered-dose inhaler during mechanical ventilation

D Georgopoulos, E Mouloudi, E Kondili… - Critical care, 2000 - Springer
The delivery of bronchodilators with metered-dose inhaler (MDI) in mechanically ventilated
patients has attracted considerable interest in recent years. This is because the use of the …

Cost-benefit comparison of aerosol bronchodilator delivery methods in hospitalized patients

AC Jasper, Z Mohsenifar, S Kahan, HS Goldberg… - Chest, 1987 - Elsevier
We compared two modes of aerosol bronchodilator delivery in 34 patients hospitalized with
obstructive airways diseases. The standard mode, therapist-administered up-draft …

Metered dose inhalers versus nebulizers for aerosol bronchodilator delivery for adult patients receiving mechanical ventilation in critical care units

A Holland, F Smith, K Penny… - Cochrane Database …, 2013 - cochranelibrary.com
Background Nebulizers and metered dose inhalers (MDI) have both been adapted for
delivering aerosol bronchodilation to mechanically ventilated patients, but there is …

Fundamentals of aerosol therapy in critical care

J Dhanani, JF Fraser, HK Chan, J Rello, J Cohen… - Critical Care, 2016 - Springer
Drug dosing in critically ill patients is challenging due to the altered drug pharmacokinetics–
pharmacodynamics associated with systemic therapies. For many drug therapies, there is …

Not all nebulizers are created equal: Considerations in choosing a nebulizer for aerosol delivery during mechanical ventilation

R MacLoughlin, I Martin-Loeches - Expert Review of Respiratory …, 2023 - Taylor & Francis
Introduction Aerosol therapy is commonly prescribed in the mechanically ventilated patient.
Jet nebulizers (JN) and vibrating mesh nebulizers (VMN) are the most common nebulizer …