Adequate blood supply to the uterine-placental region is crucial to ensure the transport of
oxygen and nutrients to the growing fetus. Multiple factors intervene to achieve appropriate …

The central role of inflammatory processes in labour and delivery is now well-recognised.
However, the biomolecular, immunological and endocrine mechanisms involved in the …

Infertility and reproductive-associated disease are global problems in the world today
affecting millions of women. A successful pregnancy requires a healthy uterus ready to …

Estrogen and progesterone play pivotal roles in the regulation of pregnancy and parturition.
These steroids cause dramatic changes the maternal physiology which advantage the …

Estrogen plays an important role in the regulation of cardiovascular physiology and the
immune system by inducing direct effects on multiple cell types including immune and …

The steroid hormone progesterone (P), acting via the progesterone receptor (PR) isoforms,
PR‐A and PR‐B, exerts a profound influence on uterine functions during early gestation. In …

During pregnancy, the maternal cardiovascular system undergoes significant changes,
including increased heart rate, cardiac output, plasma volume, and uteroplacental blood …

Pregnancy is associated with physiological adjustments in order to allow adequate growth
and fetal development. In particular, steroids are necessary to maintain in balance …

Objective To review current knowledge regarding estrogen biosynthesis, its regulation and
action, specifically concerning local as opposed to remote effects of this hormone, and to …

Purposes This review is to challenge current concepts of women's reproduction with its
cultural over-emphasis on estrogen and positive actions, while progesterone tends to be …