Head and neck cancer (HNC) affects over 890,000 people annually worldwide and has a
mortality rate of 50%. Aside from poor survival, HNC pain impairs eating, drinking, and …

BACKGROUND: Pain is one of the first presenting symptoms in patients with head and neck
cancer, who often develop chronic and debilitating pain as the disease progresses. Pain is …

Head and neck squamous cell carcinoma (HNSCC) patients report severe function-induced
pain at the site of the primary tumor. The current hypothesis is that oral cancer pain is …

Cancer pain is an ever-present public health concern. With innovations in treatment, cancer
patients are surviving longer, but uncontrollable pain creates a poor quality of life for these …

Personalised and targeted interventions have revolutionised cancer treatment and
dramatically improved survival rates in recent decades. Nonetheless, effective pain …

The incidence of pain in cancer patients during diagnosis and treatment is exceedingly high.
Although advances in cancer detection and therapy have improved patient prognosis …

Oral cancers are often severely painful and clinically difficult to manage. Few researchers
have investigated the neurobiologic factors responsible for cancer pain; however, the study …

Oral pain due to cancer and associated treatments is common. The prevalence and severity
of oral cancer is high. Painful oral mucositis develops in head and neck cancer patients …

The incidence of oral cancer in the United States is increasing, especially in young people
and women. Patients with oral cancer report severe functional pain. Using a patient cohort …

Patients with oral cancer report severe pain during function. Inflammation plays a role in the
oral cancer microenvironment; however, the role of immune cells and associated secretion …