Tacrine (Amino tetrahydroacridine hydrochloride hydrate) is a non-competitive and
reversible inhibitor of acetylcholine esterase, and butylcholinesterase. Alzheimer's disease …

Our previous studies demonstrate that a non-cholinesterase inhibitor (AChEI) compound
catalpol, purified from a traditional Chinese medicinal herb Rehmannia glutinosa, could …

Alzheimer's disease (AD), one of the most common neurodegenerative diseases, has no
effective treatment. We studied the potential effects of tetramethylpyrazine (TMP), an alkaloid …

The hippocampal gamma oscillation is important for cognitive function, and its deficit is
related to cognitive impairment in Alzheimer's disease (AD). Recently, it has been …

The pathogenesis of Alzheimer's disease (AD) has been linked to the deficiency of
neurotransmitter acetylcholine (ACh) in the brain, and the main treatment strategy for …

Alzheimer's disease (AD) is the primary cause of dementia. There is no effective treatment.
Amyloid-β peptide (Aβ) plays an important role in the pathogenesis and thus strategies …

Summary Aims To investigate whether Meserine, a novel phenylcarbamate derivative of (−)‐
meptazinol, possesses beneficial activities against cholinergic deficiency and …

Alzheimer's disease (AD) is a severe neurodegenerative disease for which there is currently
no effective treatment. This study investigated whether treatment with the herbal formula …

Therapeutic approach for Alzheimer's disease (AD) is still deficient. To find active
compounds from herbal medicine is of interest in the alleviation of AD symptoms. This study …

Abstract Background Histone deacetylases (HDACs) target various genes responsible for
cognitive functions. However, chromatin readers, particularly bromodomain-containing …