Acetoacetate improves memory in Alzheimer's mice via promoting brain-derived neurotrophic factor and inhibiting inflammation
XJ Wu, QQ Shu, B Wang, L Dong… - American Journal of …, 2022 - journals.sagepub.com
The ketone bodies, especially the β-hydroxybutyrate, had been shown to modulate the
function of the central nervous system and prevent the pathological progression of …
function of the central nervous system and prevent the pathological progression of …
The protective effect of icariin on mitochondrial transport and distribution in primary hippocampal neurons from 3× Tg-AD mice
Y Chen, S Han, X Huang, J Ni, X He - International journal of molecular …, 2016 - mdpi.com
Icariin, a pharmacologically active component isolated from the Chinese herb Epimedium,
has been shown to improve spatial learning and memory abilities in Alzheimer's disease …
has been shown to improve spatial learning and memory abilities in Alzheimer's disease …
Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer's-Like …
Neurodegeneration implies progressive neuronal loss and neuroinflammation further
contributing to pathology progression. It is a feature of many neurological disorders, most …
contributing to pathology progression. It is a feature of many neurological disorders, most …
Tacrine (10)-hupyridone, a dual-binding acetylcholinesterase inhibitor, potently attenuates scopolamine-induced impairments of cognition in mice
H Chen, S Xiang, L Huang, J Lin, S Hu, SH Mak… - Metabolic Brain …, 2018 - Springer
Abstract Tacrine (10)-hupyridone (A10E) was designed as a dual-binding
acetylcholinesterase (AChE) inhibitor from the modification of tacrine and a fragment of …
acetylcholinesterase (AChE) inhibitor from the modification of tacrine and a fragment of …
Avenanthramide-C restores impaired plasticity and cognition in Alzheimer's disease model mice
VS Ramasamy, M Samidurai, HJ Park, M Wang… - Molecular …, 2020 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
cognitive decline and dementia with no effective treatment. Here, we investigated a novel …
cognitive decline and dementia with no effective treatment. Here, we investigated a novel …
Dilinoleoylphosphatidylcholine ameliorates scopolamine-induced impairment of spatial learning and memory by targeting α7 nicotinic ACh receptors
T Yaguchi, T Nagata, T Nishizaki - Life sciences, 2009 - Elsevier
AIMS: The present study was conducted to understand the role of 1, 2-dilynoleoyl-sn-glycero-
3-phosphocholine (DLPhtCho) in cognitive functions. MAIN METHODS: Two-electrode …
3-phosphocholine (DLPhtCho) in cognitive functions. MAIN METHODS: Two-electrode …
Tacrine–hydrogen sulfide donor hybrid ameliorates cognitive impairment in the aluminum chloride mouse model of Alzheimer's disease
X Cheng, J Gu, Y Pang, J Liu, T Xu, X Li… - ACS Chemical …, 2019 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by progressive
loss of memory and cognitive function, and is associated with the deficiency of synaptic …
loss of memory and cognitive function, and is associated with the deficiency of synaptic …
Indomethacin enhances learning and memory potential by interacting with CaMKII
T Kanno, T Yaguchi, T Nagata… - Journal of cellular …, 2012 - Wiley Online Library
The present study examined the effect of indomethacin (IM), a cyclooxygenase inhibitor, on
learning and memory functions. IM activated Ca2+/calmodulin‐dependent protein kinase II …
learning and memory functions. IM activated Ca2+/calmodulin‐dependent protein kinase II …
Direct pharmacological Akt activation rescues Alzheimer's disease like memory impairments and aberrant synaptic plasticity
Amyloid β (Aβ) is a key mediator for synaptic dysfunction and cognitive impairment
implicated in Alzheimer's disease (AD). However, the precise mechanism of the toxic effect …
implicated in Alzheimer's disease (AD). However, the precise mechanism of the toxic effect …
Effects of KakamGoBonHwan (KGBH) on inhibition of impairment of learning and memory, and acetylcholinesterase in amnesia mice
IC Jung, SR Lee, SY Ha - Journal of Oriental Neuropsychiatry, 2002 - koreascience.kr
Alzheimer's disease (AD) is a progressive neurodegenerative disease, which is
pathologically characterized by neuritic plaques and neurofibrillary tangles associated with …
pathologically characterized by neuritic plaques and neurofibrillary tangles associated with …