Engineered cardiac tissues derived from human induced pluripotent stem cells offer unique
opportunities for patient-specific disease modeling, drug discovery and cardiac repair. Since …

Engineering of three-dimensional (3D) tissues is a promising approach for restoring
diseased or dysfunctional myocardium with a functional replacement. However, a major …

Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac
regeneration. Recent advances in 3-dimensional bioprinting technology using …

The promise of cardiac tissue engineering is in the ability to recapitulate in vitro the
functional aspects of a healthy heart and disease pathology as well as to design …

Cardiovascular diseases are the major cause of death worldwide. The heart has limited
capacity of regeneration, therefore, transplantation is the only solution in some cases …

Cardiovascular diseases (CVDs) are the leading causes of mortality globally that demand
the application of tissue engineering strategies to repair damaged tissues. Conventional …

[Frontiers in Bioscience 17, 1533-1550, January 1, 2012] 1533 Cardiac tissue engineering:
current state and perspectives Loraine Page 1 [Frontiers in Bioscience 17, 1533-1550 …

Introduction: A thorough understanding of the cellular and muscle fiber orientation in left
ventricular cardiac tissue is of paramount importance for the generation of artificial cardiac …

During an average individual's lifespan, the human heart pumps nearly 200 million liters of
blood delivered by approximately 3 billion heartbeats. Therefore, it is not surprising that …

Numerous microfabrication approaches have been developed to recapitulate
morphologically and functionally organized tissue microarchitectures in vitro; however, the …