The pathogenesis of multiple sclerosis (MS) is mediated by massive infiltration of myelin-
specific T cells into the central nervous system (CNS). Self-reactive CD4+ T helper (Th) cells …

Multiple sclerosis (MS) is a devastating autoimmune demyelinating disease of the central
nervous system (CNS). This study investigated whether expression and activity of the …

Multiple sclerosis (MS) pathology is marked by the massive infiltration of myelin-specific T
cells into the central nervous system (CNS). During active disease, pro-inflammatory …

Multiple sclerosis (MS) pathology is marked by the massive infiltration of myelin‐specific T
cells into the CNS. Hallmarks of T helper (Th) cells during active disease are pro …

Multiple sclerosis (MS) is a T‐cell mediated autoimmune disease of the CNS, possessing
both immune and neurodegenerative events that lead to disability. Adoptive transfer (AT) of …

Multiple sclerosis (MS), the most common chronic autoimmune inflammatory disease of the
central nervous system (CNS), is characterized by demyelination and neurodegeneration. In …

Multiple sclerosis (MS) is best understood as an inflammatory disease of the central nervous
system (CNS) white matter characterized by demyelination, focal T cell and macrophage …

Multiple sclerosis (MS) is an autoimmune disease characterized by immune-mediated
attacks on the central nervous system (CNS), resulting in demyelination and recurring T-cell …

Calpain activity and expression at the protein level were examined in inflammatory cells,
activated microglia, and astrocytes prior to or at onset of symptomatic experimental allergic …

Background and Objectives Multiple sclerosis (MS) is an inflammatory demyelinating
disease of the CNS. CD8+ T cells are prominently found at inflammatory sites. Recent …