[HTML][HTML] Pathogenic mechanisms associated with different clinical courses of multiple sclerosis
H Lassmann - Frontiers in immunology, 2019 - frontiersin.org
In the majority of patients multiple sclerosis starts with a relapsing remitting course (RRMS),
which may at later times transform into secondary progressive disease (SPMS). In a minority …
which may at later times transform into secondary progressive disease (SPMS). In a minority …
Involvement of calpain in the process of Jurkat T cell chemotaxis
JT Butler, S Samantaray, CC Beeson… - Journal of …, 2009 - Wiley Online Library
Massive T cell infiltration into the central nervous system is a hallmark of multiple sclerosis
(MS) and its rodent model experimental autoimmune encephalomyelitis (EAE), resulting in …
(MS) and its rodent model experimental autoimmune encephalomyelitis (EAE), resulting in …
[HTML][HTML] Recent advances in understanding multiple sclerosis
Emerging data point to important contributions of both autoimmune inflammation and
progressive degeneration in the pathophysiology of multiple sclerosis (MS). Unfortunately …
progressive degeneration in the pathophysiology of multiple sclerosis (MS). Unfortunately …
Clues to the immunopathogenesis of multiple sclerosis by investigating untreated patients during the very early stage of disease
M Söderström - Neurological Sciences, 2001 - Springer
Plethora of abnormalities of the immune system has been described in multiple sclerosis
(MS). They include a number of myelin antigens (eg MBP, MOG, PLP, MAG), the presence of …
(MS). They include a number of myelin antigens (eg MBP, MOG, PLP, MAG), the presence of …
[HTML][HTML] Distinct inflammatory profiles of myelin-reactive T cells from patients with multiple sclerosis
Myelin-reactive T cells have been identified in patients with multiple sclerosis (MS) and
healthy subjects with comparable frequencies, but the functional programs of self-reactive T …
healthy subjects with comparable frequencies, but the functional programs of self-reactive T …
Cathepsin B inhibitor alleviates Th1, Th17, and Th22 transcription factor signaling dysregulation in experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory infiltration
in association with demyelination in the central nervous system. Among the factors involved …
in association with demyelination in the central nervous system. Among the factors involved …
T-cells in multiple sclerosis
C Severson, DA Hafler - 2009 - Springer
Multiple sclerosis (MS) is a multifocal demyelinating disease of the central nervous system
pathologically characterized by lesions of infiltrating macrophages and T cells. Multiple lines …
pathologically characterized by lesions of infiltrating macrophages and T cells. Multiple lines …
[HTML][HTML] Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS)
characterized by multi-focal demyelination, axonal loss, and immune cell infiltration …
characterized by multi-focal demyelination, axonal loss, and immune cell infiltration …
An elevated matrix metalloproteinase (MMP) in an animal model of multiple sclerosis is protective by affecting Th1/Th2 polarization
A Weaver, AG Da Silva, RK Nuttall… - The FASEB …, 2005 - Wiley Online Library
Inflammation in multiple sclerosis and its animal model, experimental autoimmune
encephalomyelitis (EAE), is manifested by changes in matrix metalloproteinase (MMP) …
encephalomyelitis (EAE), is manifested by changes in matrix metalloproteinase (MMP) …
Multiple sclerosis immunology: the healthy immune system vs the MS immune system
LH Kasper, J Shoemaker - Neurology, 2010 - AAN Enterprises
Multiple sclerosis (MS) is a debilitating autoimmune disease characterized by both
inflammation and axonal degeneration. The resulting demyelination and subsequent …
inflammation and axonal degeneration. The resulting demyelination and subsequent …