In the majority of patients multiple sclerosis starts with a relapsing remitting course (RRMS),
which may at later times transform into secondary progressive disease (SPMS). In a minority …

Massive T cell infiltration into the central nervous system is a hallmark of multiple sclerosis
(MS) and its rodent model experimental autoimmune encephalomyelitis (EAE), resulting in …

Emerging data point to important contributions of both autoimmune inflammation and
progressive degeneration in the pathophysiology of multiple sclerosis (MS). Unfortunately …

Plethora of abnormalities of the immune system has been described in multiple sclerosis
(MS). They include a number of myelin antigens (eg MBP, MOG, PLP, MAG), the presence of …

Myelin-reactive T cells have been identified in patients with multiple sclerosis (MS) and
healthy subjects with comparable frequencies, but the functional programs of self-reactive T …

Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory infiltration
in association with demyelination in the central nervous system. Among the factors involved …

Multiple sclerosis (MS) is a multifocal demyelinating disease of the central nervous system
pathologically characterized by lesions of infiltrating macrophages and T cells. Multiple lines …

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS)
characterized by multi-focal demyelination, axonal loss, and immune cell infiltration …

Inflammation in multiple sclerosis and its animal model, experimental autoimmune
encephalomyelitis (EAE), is manifested by changes in matrix metalloproteinase (MMP) …

Multiple sclerosis (MS) is a debilitating autoimmune disease characterized by both
inflammation and axonal degeneration. The resulting demyelination and subsequent …