BACKGROUND: COPD patients have varying degrees of airways disease and emphysema.
CT scanning can differentiate these pathological subtypes. We evaluated airway dimensions …

Objective: It is not well known whether there is heterogeneity in the airway dimensions at
different anatomic locations in individual patients with COPD. The first objective was to …

Background CT scan measures of emphysema and airway disease have been correlated
with lung function in cohorts of subjects with a range of COPD severity. The contribution of …

Background COPD is a heterogeneous disease characterized by airflow obstruction and
diagnosed by lung function. CT imaging is emerging as an important, noninvasive tool in …

Background The contribution and role of emphysema and small airways disease in causing
expiratory airflow limitation in COPD is controversial. Methods We obtained high-resolution …

Rationale Bronchodilator responsiveness (BDR) is a common but variable phenomenon in
COPD. The CT characteristics of airway dimensions that differentiate COPD subjects with …

Airway remodeling is extremely important in the pathophysiology of chronic obstructive
pulmonary disease (COPD). Since the site and nature of airflow obstruction was described …

Background: Chronic obstructive pulmonary disease (COPD) is characterized by airflow
obstruction caused by emphysema or airway narrowing, or both. Recently airway …

Background and objective: COPD and bronchial asthma are chronic airway diseases with a
different pathogenesis. Comparisons of differences in airway calibre by bronchial generation …

Background Computed tomography (CT) phenotypic characterization helps in
understanding the clinical diversity of chronic obstructive pulmonary disease (COPD) …