An evolutionary perspective on FoxP2: strictly for the birds?
C Scharff, S Haesler - Current opinion in neurobiology, 2005 - Elsevier
FoxP2 mutations in humans are associated with a disorder that affects both the
comprehension of language and its production, speech. This discovery provided the first …
comprehension of language and its production, speech. This discovery provided the first …
Birdsong decreases protein levels of FoxP2, a molecule required for human speech
Cognitive and motor deficits associated with language and speech are seen in humans
harboring FOXP2 mutations. The neural bases for FOXP2 mutation-related deficits are …
harboring FOXP2 mutations. The neural bases for FOXP2 mutation-related deficits are …
FoxP2 expression in avian vocal learners and non-learners
S Haesler, K Wada, A Nshdejan… - Journal of …, 2004 - Soc Neuroscience
Most vertebrates communicate acoustically, but few, among them humans, dolphins and
whales, bats, and three orders of birds, learn this trait. FOXP2 is the first gene linked to …
whales, bats, and three orders of birds, learn this trait. FOXP2 is the first gene linked to …
[HTML][HTML] FOXP2 as a molecular window into speech and language
Rare mutations of the FOXP2 transcription factor gene cause a monogenic syndrome
characterized by impaired speech development and linguistic deficits. Recent genomic …
characterized by impaired speech development and linguistic deficits. Recent genomic …
Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language
In 2001, a point mutation in the forkhead box P2 (FOXP2) coding sequence was identified as
the basis of an inherited speech and language disorder suffered by members of the family …
the basis of an inherited speech and language disorder suffered by members of the family …
FOXP2 and the role of cortico-basal ganglia circuits in speech and language evolution
W Enard - Current opinion in neurobiology, 2011 - Elsevier
PURPOSE OF THE REVIEW: A reduced dosage of the transcription factor FOXP2 leads to
speech and language impairments probably owing to deficits in cortical and subcortical …
speech and language impairments probably owing to deficits in cortical and subcortical …
The structure of innate vocalizations in Foxp2‐deficient mouse pups
S Gaub, M Groszer, SE Fisher… - Genes, Brain and …, 2010 - Wiley Online Library
Heterozygous mutations of the human FOXP2 gene are implicated in a severe speech and
language disorder. Aetiological mutations of murine Foxp2 yield abnormal synaptic plasticity …
language disorder. Aetiological mutations of murine Foxp2 yield abnormal synaptic plasticity …
[HTML][HTML] Striatal FoxP2 Is Actively Regulated during Songbird Sensorimotor Learning
Background Mutations in the FOXP2 transcription factor lead to language disorders with
developmental onset. Accompanying structural abnormalities in cortico-striatal circuitry …
developmental onset. Accompanying structural abnormalities in cortico-striatal circuitry …
FoxP2 in Song-Learning Birds and Vocal-Learning Mammals
DM Webb, J Zhang - Journal of Heredity, 2005 - academic.oup.com
FoxP2 is the first identified gene that is specifically involved in speech and language
development in humans. Population genetic studies of FoxP2 revealed a selective sweep in …
development in humans. Population genetic studies of FoxP2 revealed a selective sweep in …
Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction
Humans and songbirds are two of the rare animal groups that modify their innate
vocalizations. The identification of FOXP2 as the monogenetic locus of a human speech …
vocalizations. The identification of FOXP2 as the monogenetic locus of a human speech …