An evolutionary perspective on FoxP2: strictly for the birds?

C Scharff, S Haesler - Current opinion in neurobiology, 2005 - Elsevier
FoxP2 mutations in humans are associated with a disorder that affects both the
comprehension of language and its production, speech. This discovery provided the first …

Birdsong decreases protein levels of FoxP2, a molecule required for human speech

JE Miller, E Spiteri, MC Condro… - Journal of …, 2008 - journals.physiology.org
Cognitive and motor deficits associated with language and speech are seen in humans
harboring FOXP2 mutations. The neural bases for FOXP2 mutation-related deficits are …

FoxP2 expression in avian vocal learners and non-learners

S Haesler, K Wada, A Nshdejan… - Journal of …, 2004 - Soc Neuroscience
Most vertebrates communicate acoustically, but few, among them humans, dolphins and
whales, bats, and three orders of birds, learn this trait. FOXP2 is the first gene linked to …

[HTML][HTML] FOXP2 as a molecular window into speech and language

SE Fisher, C Scharff - Trends in Genetics, 2009 - cell.com
Rare mutations of the FOXP2 transcription factor gene cause a monogenic syndrome
characterized by impaired speech development and linguistic deficits. Recent genomic …

Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language

SA White, SE Fisher, DH Geschwind… - Journal of …, 2006 - Soc Neuroscience
In 2001, a point mutation in the forkhead box P2 (FOXP2) coding sequence was identified as
the basis of an inherited speech and language disorder suffered by members of the family …

FOXP2 and the role of cortico-basal ganglia circuits in speech and language evolution

W Enard - Current opinion in neurobiology, 2011 - Elsevier
PURPOSE OF THE REVIEW: A reduced dosage of the transcription factor FOXP2 leads to
speech and language impairments probably owing to deficits in cortical and subcortical …

The structure of innate vocalizations in Foxp2‐deficient mouse pups

S Gaub, M Groszer, SE Fisher… - Genes, Brain and …, 2010 - Wiley Online Library
Heterozygous mutations of the human FOXP2 gene are implicated in a severe speech and
language disorder. Aetiological mutations of murine Foxp2 yield abnormal synaptic plasticity …

[HTML][HTML] Striatal FoxP2 Is Actively Regulated during Songbird Sensorimotor Learning

I Teramitsu, A Poopatanapong, S Torrisi, SA White - PloS one, 2010 - journals.plos.org
Background Mutations in the FOXP2 transcription factor lead to language disorders with
developmental onset. Accompanying structural abnormalities in cortico-striatal circuitry …

FoxP2 in Song-Learning Birds and Vocal-Learning Mammals

DM Webb, J Zhang - Journal of Heredity, 2005 - academic.oup.com
FoxP2 is the first identified gene that is specifically involved in speech and language
development in humans. Population genetic studies of FoxP2 revealed a selective sweep in …

Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction

I Teramitsu, LC Kudo, SE London… - Journal of …, 2004 - Soc Neuroscience
Humans and songbirds are two of the rare animal groups that modify their innate
vocalizations. The identification of FOXP2 as the monogenetic locus of a human speech …